SCHEMBL5669701

SCHEMBL5669701

CO[Si](CCCCCCCCCCCCSSCCCCCCCCCCCC[Si](OC)(OC)OC)(OC)OC

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5671814 1.00 LMNA (0.41) LMNA
SCHEMBL308648 0.97 LMNA (0.38) LMNA
SCHEMBL29001377 0.91 LMNA (0.38) LMNA
SCHEMBL6905611 0.91 LMNA (0.38) LMNA
SCHEMBL79932 0.90 LMNA (0.39) LMNA
SCHEMBL380626 0.88 LMNA (0.35) LMNA
SCHEMBL309628 0.88 LMNA (0.35) LMNA
SCHEMBL17882508 0.85 LMNA (0.36) LMNA
SCHEMBL9859842 0.85 LMNA (0.41) LMNA
SCHEMBL3741069 0.84 LMNA (0.50) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0995775-B1 Preparation of stach reinforced rubber, vulcanized rubber tire and article of manufacture GOODYEAR TIRE & RUBBER (US) 2004-08-18 EP claimed
EP-0994150-B1 Preparation of reinforced rubber GOODYEAR TIRE & RUBBER (US) 2004-03-24 EP claimed
US-6458871-B2 MIXING A ORGANOSILANE DISULFIDE, A RUBBER AND A REINFORCING FILLER THE GOODYEAR TIRE & RUBBER COMPANY 2002-10-01 US claimed
US-6384127-B2 MIXTURE CONTAINING ORGANOSILANE DISULFIDE COMPOUND THE GOODYEAR TIRE & RUBBER COMPANY 2002-05-07 US claimed
US-20020019473-A1 SILICA REINFORCED RUBBER COMPOSITION AND USE IN TIRES GOODYEAR TIRE & RUBBER COMPANY, THE 2002-02-14 US claimed
US-20010034392-A1 Preparation of reinforced rubber and use in tires THE GOODYEAR TIRE & RUBBER COMPANY 2001-10-25 US claimed
US-20010031803-A1 Preparation of starch reinforced rubber and use thereof in tires THE GOODYEAR TIRE & RUBBER COMPANY 2001-10-18 US claimed
US-6156822-A Prepared reinforced elastomer, elastomer composite and tire having component thereof THE GOODYEAR TIRE & RUBBER COMPANY (US) 2000-12-05 US claimed
EP-1002835-A2 Reinforced elastomer preparation and tire having component thereof THE GOODYEAR TIRE & RUBBER COMPANY (US) 2000-05-24 EP claimed
EP-1002836-A1 Method for preparing in-situ-reinforced elastomer THE GOODYEAR TIRE & RUBBER COMPANY (US) 2000-05-24 EP claimed
EP-1000960-A1 Preparation of reinforced elastomer THE GOODYEAR TIRE & RUBBER COMPANY (US) 2000-05-17 EP claimed
EP-0995775-A1 Preparation of starch reinforced rubber THE GOODYEAR TIRE & RUBBER COMPANY (US) 2000-04-26 EP claimed
EP-0994150-A1 Preparation of reinforced rubber THE GOODYEAR TIRE & RUBBER COMPANY (US) 2000-04-19 EP claimed
EP-0732362-B1 Silica reinforced rubber composition and use in tyres GOODYEAR TIRE & RUBBER (US) 1999-06-02 EP claimed
EP-0845493-A1 Silica reinforced rubber composition and use in tires THE GOODYEAR TIRE & RUBBER COMPANY (US) 1998-06-03 EP claimed
US-5580919-A ORGANOSILANE DISULFIDE COUPLER THE GOODYEAR TIRE & RUBBER COMPANY (US) 1996-12-03 US claimed
EP-0732362-A1 Silica reinforced rubber composition and use in tyres THE GOODYEAR TIRE & RUBBER COMPANY (US) 1996-09-18 EP claimed
EP-1293529-B1 Elastomer/reinforcing filler composite GOODYEAR TIRE & RUBBER (US) 2006-12-13 EP disclosed
US-5580919-A ORGANOSILANE DISULFIDE COUPLER THE GOODYEAR TIRE & RUBBER COMPANY (US) 1996-12-03 US disclosed
EP-0732362-A1 Silica reinforced rubber composition and use in tyres THE GOODYEAR TIRE & RUBBER COMPANY (US) 1996-09-18 EP disclosed