Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 11/20 | 0.36 |
| ▸ | BRAF | P15056 | 3/20 | 0.33 |
| ▸ | KDR | P35968 | 3/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5669293 | 1.00 | CETP (0.36) | CETPBRAFKDRSCN9AIDO1 | |
| SCHEMBL1899843 | 0.93 | CETP (0.34) | CETPSCN9AKCNH2MAPK1 | |
| SCHEMBL5669603 | 0.93 | CETP (0.34) | CETPSCN9AKCNH2MAPK1 | |
| SCHEMBL6281114 | 0.89 | CETP (0.39) | CETPIDO1TDO2KCNH2 | |
| SCHEMBL6568885 | 0.89 | CETP (0.39) | CETPIDO1TDO2KCNH2 | |
| SCHEMBL5670008 | 0.88 | CETP (0.37) | CETPBRAFKDRSCN9AIDO1 | |
| SCHEMBL6569043 | 0.88 | CETP (0.37) | CETPBRAFKDRSCN9AIDO1 | |
| SCHEMBL6568980 | 0.85 | CETP (0.44) | CETP | |
| SCHEMBL6566955 | 0.85 | CETP (0.47) | CETP | |
| SCHEMBL6568209 | 0.85 | CETP (0.47) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670446-A2 | METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION | JAPAN TOBACCO INC. (JP) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005030185-A2 | METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION | JAPAN TOBACCO INC. (JP) | 2005-04-07 | — | — | WO | disclosed |
| EP-1469831-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING A SOLID AMORPHOUS DISPERSION OF CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS | Pfizer Products Inc. (US) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003063832-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING A SOLID AMORPHOUS DISPERSION OF CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS | PFIZER PRODUCTS INC. (US) | 2003-08-07 | — | — | WO | disclosed |