Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 8/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.34 |
| ▸ | BRAF | P15056 | 3/20 | 0.34 |
| ▸ | KDR | P35968 | 3/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5670008 | 1.00 | CETP (0.37) | CETPIDO1TDO2P2RY1BRAF | |
| SCHEMBL6567135 | 0.93 | CETP (0.36) | CETPP2RY1KDRSCN9APNMT | |
| SCHEMBL5670143 | 0.93 | CETP (0.36) | CETPP2RY1KDRSCN9APNMT | |
| SCHEMBL5669293 | 0.88 | CETP (0.36) | CETPIDO1TDO2BRAFKDR | |
| SCHEMBL5669869 | 0.88 | CETP (0.36) | CETPIDO1TDO2BRAFKDR | |
| SCHEMBL6566052 | 0.88 | IDO1 (0.43) | CETPIDO1TDO2 | |
| SCHEMBL6568878 | 0.88 | IDO1 (0.43) | CETPIDO1TDO2 | |
| SCHEMBL6277313 | 0.86 | CETP (0.43) | CETPIDO1TDO2 | |
| SCHEMBL1565225 | 0.86 | CETP (0.41) | CETPIDO1TDO2 | |
| SCHEMBL5671186 | 0.86 | CETP (0.41) | CETPIDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1469831-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING A SOLID AMORPHOUS DISPERSION OF CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS | Pfizer Products Inc. (US) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003063832-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING A SOLID AMORPHOUS DISPERSION OF CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS | PFIZER PRODUCTS INC. (US) | 2003-08-07 | — | — | WO | disclosed |