Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.60 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2338691 | 0.83 | KCNA5 (0.73) | KCNA5SLC18A3MMP1MMP9MMP13 | |
| SCHEMBL2332192 | 0.83 | KCNA5 (0.73) | KCNA5SLC18A3MMP1MMP9MMP13 | |
| SCHEMBL1682280 | 0.72 | HTR2A (0.48) | HTTPGRHTR2AHTR2CRORC | |
| SCHEMBL14854003 | 0.72 | KCNA5 (0.59) | KCNA5PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL14842776 | 0.72 | KCNA5 (0.59) | KCNA5PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL10511383 | 0.71 | SLC18A3 (0.62) | KCNA5SLC18A3HTTMMP1MMP9 | |
| SCHEMBL10573537 | 0.71 | SLC18A3 (0.71) | KCNA5SLC18A3HTTALDH1A1MEN1 | |
| SCHEMBL18386875 | 0.71 | SLC18A3 (0.71) | KCNA5SLC18A3HTTALDH1A1MEN1 | |
| SCHEMBL2341562 | 0.69 | PSEN1 (0.57) | KCNA5MMP1MMP9MMP13PSEN1 | |
| SCHEMBL2335388 | 0.69 | PSEN1 (0.57) | KCNA5MMP1MMP9MMP13PSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1723102-A2 | N-SUBSTITUTED BENZENE SULFONAMIDES | Elan Pharmaceuticals, Inc. (US) | 2006-11-22 | — | — | EP | disclosed |
| WO-2005090296-A2 | N-SUBSTITUTED BENZENE SULFONAMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2005-09-29 | — | — | WO | disclosed |