SCHEMBL5670846

SCHEMBL5670846

Cc1cccc(Oc2cccc(C(NC[C@@H](O)C(F)(F)F)c3cccc(OC(F)(F)C(F)F)c3)c2)c1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6571432 1.00 CETP (0.56) CETP
SCHEMBL6570148 0.95 CETP (0.57) CETP
SCHEMBL6571649 0.93 CETP (0.57) CETP
SCHEMBL5670123 0.93 CETP (0.57) CETP
SCHEMBL6570035 0.92 CETP (0.52) CETP
SCHEMBL6566032 0.90 CETP (0.61) CETP
SCHEMBL5670011 0.90 CETP (0.61) CETP
SCHEMBL5669965 0.90 CETP (0.54) CETP
SCHEMBL7808089 0.90 CETP (0.54) CETP
SCHEMBL5670036 0.90 CETP (0.54) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1670446-A2 METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION JAPAN TOBACCO INC. (JP) 2006-06-21 EP claimed
WO-2005030185-A2 METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION JAPAN TOBACCO INC. (JP) 2005-04-07 WO claimed
EP-1670446-A2 METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION JAPAN TOBACCO INC. (JP) 2006-06-21 EP disclosed
WO-2005030185-A2 METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION JAPAN TOBACCO INC. (JP) 2005-04-07 WO disclosed