Maleic Anhydride

Maleic Anhydride

SCHEMBL5670906

C/C(=C/C(=O)O)C(=O)O.O=C1C=CC(=O)O1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTT P42858 4/20 0.41
KMT2A Q03164 1/20 0.40
ALDH1A1 P00352 5/20 0.39
MAPT P10636 4/20 0.39
KDM4E B2RXH2 3/20 0.39
POLB P06746 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
PKM P14618 2/20 0.39
AKR1C3 P42330 1/20 0.35
CYP2C9 P11712 1/20 0.35
LMNA P02545 1/20 0.31
APEX1 P27695 2/20 0.31
PARP1 P09874 2/20 0.30
PARP15 Q460N3 1/20 0.30
PARP10 Q53GL7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Maleic Anhydride SCHEMBL11597127 1.00 HTT (0.41) HTTKMT2AALDH1A1MAPTKDM4E
Styrene SCHEMBL16618108 0.84 HTT (0.48) HTTKMT2AALDH1A1MAPTKDM4E
Styrene SCHEMBL16618106 0.84 HTT (0.48) HTTKMT2AALDH1A1MAPTKDM4E
Maleic Anhydride SCHEMBL2438117 0.83 AKR1C3 (0.38) KMT2AMAPTAKR1C3CYP2C9APEX1
Maleic Anhydride SCHEMBL8044378 0.83 HTT (0.34) HTTKMT2AALDH1A1MAPTKDM4E
Maleic Anhydride SCHEMBL8745637 0.78 FFAR3 (0.41) KMT2AALDH1A1CYP2C9
SCHEMBL28517 0.78
SCHEMBL623803 0.78 HTT (0.45) HTTKMT2AALDH1A1MAPTKDM4E
SCHEMBL5893 0.78
SCHEMBL623108 0.78 HTT (0.45) HTTKMT2AALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4115370-A CROSSLINKING WITH VINYL MONOMERS SNIA VISCOSA SOCIETA' NAZIONALE INDUSTRIA APPLICAZIONI VISCOSA S.P.A. (IT) 1978-09-19 US claimed
EP-1265972-A4 LUMINESCENT GEL COATS AND MOLDABLE RESINS ORION 21 A D PTY LTD (AU) 2006-12-20 EP disclosed
EP-1265972-A1 LUMINESCENT GEL COATS AND MOLDABLE RESINS Orion 21 A.D. Pty Limited (AU) 2002-12-18 EP disclosed
WO-2001060943-A1 LUMINESCENT GEL COATS AND MOLDABLE RESINS ORION 21 A.D. PTY LIMITED (AU) 2001-08-23 WO disclosed