Maleic Anhydride

Maleic Anhydride

SCHEMBL8044378

C/C(=C/C(=O)O)C(=O)OC(=O)/C(C)=C\C(=O)O.O=C1C=CC(=O)O1

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.34
KMT2A Q03164 1/20 0.34
POLB P06746 2/20 0.33
MAPT P10636 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
PKM P14618 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Maleic Anhydride SCHEMBL11597127 0.83 HTT (0.41) HTTKMT2APOLBMAPTTDP1
Maleic Anhydride SCHEMBL5670906 0.83 HTT (0.41) HTTKMT2APOLBMAPTTDP1
SCHEMBL623254 0.80 HTT (0.36) HTTKMT2APOLBMAPTTDP1
SCHEMBL20025 0.80 HTT (0.36) HTTKMT2APOLBMAPTTDP1
SCHEMBL11726610 0.77 HTT (0.38) HTTKMT2APOLBMAPTTDP1
SCHEMBL5804758 0.74 HTT (0.37) HTTKMT2APOLBMAPTTDP1
Maleic Anhydride SCHEMBL8745637 0.73 FFAR3 (0.41) KMT2AALDH1A1
SCHEMBL27961336 0.72 HTT (0.32) HTTKMT2AALDH1A1
SCHEMBL5804761 0.72 HTT (0.32) HTTKMT2AALDH1A1
SCHEMBL27531631 0.72 HTT (0.32) HTTKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0684967-B1 CURABLE COMPOSITE MATERIALS CYTEC TECH CORP (US) 2000-04-26 EP disclosed
US-5840424-A THERMOSETTABLE RESIN MATRIX AND A CONTINUOUS-FIBER REINFORCEMENT IMPREGNATED BY MATRIX; FIBERS SIZED WITH AN AROMATIC THERMOPLASTIC RESIN SELECTED FROM POLYSULFONES, IMIDIZED POLYSULFONES AND POLYISOIMIDES FIBERITE, INC. (US) 1998-11-24 US disclosed
EP-0684967-A1 CURABLE COMPOSITE MATERIALS ICI COMPOSITES INC. (US) 1995-12-06 EP disclosed
WO-1994019398-A1 CURABLE COMPOSITE MATERIALS ICI COMPOSITES INC. (US) 1994-09-01 WO disclosed