Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 7/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.48 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.37 |
| ▸ | BHMT | Q93088 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3281581 | 0.96 | GLO1 (0.62) | GLO1PTGS1GSTK1NOD1FOLH1 | |
| SCHEMBL3281589 | 0.96 | GLO1 (0.62) | GLO1PTGS1GSTK1NOD1FOLH1 | |
| SCHEMBL13405584 | 0.87 | GLO1 (0.61) | GLO1PTGS1GSTK1NOD1FOLH1 | |
| SCHEMBL3280199 | 0.87 | GLO1 (0.60) | GLO1PTGS1GSTK1NOD1FOLH1 | |
| SCHEMBL3280191 | 0.87 | GLO1 (0.60) | GLO1PTGS1GSTK1NOD1FOLH1 | |
| SCHEMBL3279946 | 0.87 | GLO1 (0.60) | GLO1PTGS1GSTK1NOD1FOLH1 | |
| SCHEMBL3281101 | 0.87 | GLO1 (0.72) | GLO1PTGS1GSTK1NOD1FOLH1 | |
| SCHEMBL3281097 | 0.87 | GLO1 (0.72) | GLO1PTGS1GSTK1NOD1FOLH1 | |
| SCHEMBL3279951 | 0.87 | GLO1 (0.60) | GLO1PTGS1GSTK1NOD1FOLH1 | |
| SCHEMBL5672831 | 0.83 | GLO1 (0.55) | GLO1PTGS1GSTK1NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1628999-A4 | INACTIVATORS AND BIVALENT INHIBITORS OF GLYOXALASE I AND METHODS OF INHIBITING TUMOR GROWTH | UNIV MARYLAND (US) | 2006-08-23 | — | — | EP | disclosed |
| EP-1628999-A2 | INACTIVATORS AND BIVALENT INHIBITORS OF GLYOXALASE I AND METHODS OF INHIBITING TUMOR GROWTH | University of Maryland, Baltimore County (US) | 2006-03-01 | — | — | EP | disclosed |
| WO-2005007079-A2 | INACTIVATORS AND BIVALENT INHIBITORS OF GLYOXALASE I AND METHODS OF INHIBITING TUMOR GROWTH | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (US) | 2005-01-27 | — | — | WO | disclosed |