Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK2 | O95069 | 2/20 | 0.61 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | DHODH | Q02127 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.53 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6349505 | 0.86 | PTPRC (0.60) | KCNK2SERPINE1HDAC1MEN1KMT2A | |
| SCHEMBL1954779 | 0.85 | MEN1 (0.72) | SERPINE1HDAC1DHODHMEN1KMT2A | |
| SCHEMBL6360570 | 0.85 | KCNK2 (0.68) | KCNK2HDAC1DHODHMEN1KMT2A | |
| SCHEMBL2272122 | 0.84 | DHODH (0.57) | KCNK2SERPINE1HDAC1DHODHMEN1 | |
| SCHEMBL2274953 | 0.82 | ACLY (0.67) | SERPINE1HDAC1DHODHMEN1KMT2A | |
| SCHEMBL16496601 | 0.82 | SERPINE1 (0.75) | SERPINE1DHODHMEN1KMT2AMAPT | |
| SCHEMBL6348543 | 0.81 | ALB (0.58) | KCNK2SERPINE1HDAC1MEN1KMT2A | |
| SCHEMBL16690896 | 0.81 | KDM4E (0.58) | SERPINE1HDAC1DHODHMAPTALDH1A1 | |
| SCHEMBL4236226 | 0.81 | MEN1 (0.74) | KCNK2DHODHMEN1KMT2ATDP1 | |
| SCHEMBL2278459 | 0.81 | HDAC2 (0.71) | SERPINE1HDAC1DHODHMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1626951-A1 | COMPOUNDS FOR USE AS A MEDICINE INCREASING THE CONTRACTILITY OF A HEART, A HEART MUSCLE OR CELLS OF A HEART MUSCLE | Procorde GmbH (DE) | 2006-02-22 | — | — | EP | disclosed |
| WO-2004101495-A1 | COMPOUNDS FOR USE AS A MEDICINE INCREASING THE CONTRACTILITY OF A HEART, A HEART MUSCLE OR CELLS OF A HEART MUSCLE | PROCORDE GMBH (DE) | 2004-11-25 | — | — | WO | disclosed |
| EP-1477475-A1 | Compounds for use as a medicine increasing the contractility of a heart, a heart muscle or cells of a heart muscle | Procorde GmbH (DE) | 2004-11-17 | — | — | EP | disclosed |