SCHEMBL5671569

SCHEMBL5671569

Nc1csc(-c2cccs2)c1-c1cccs1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
HSD17B10 Q99714 4/20 0.44
NPC1 O15118 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
KCNH2 Q12809 1/20 0.44
MAPT P10636 4/20 0.40
POLB P06746 1/20 0.40
ALOX15 P16050 1/20 0.40
KDM4E B2RXH2 5/20 0.39
ALDH1A1 P00352 4/20 0.39
EPHX2 P34913 1/20 0.39
HPGD P15428 3/20 0.38
GAA P10253 1/20 0.38
TSHR P16473 1/20 0.38
LTA4H P09960 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7719094 0.82 MEN1 (0.46) MEN1KMT2AHSD17B10NPC1CYP1A2
Iodide SCHEMBL30577894 0.80 MEN1 (0.44) MEN1KMT2AHSD17B10NPC1CYP1A2
SCHEMBL4613555 0.76 MEN1 (0.37) MEN1KMT2AHSD17B10NPC1CYP1A2
SCHEMBL4586849 0.76 MEN1 (0.37) MEN1KMT2AHSD17B10NPC1CYP1A2
SCHEMBL5533182 0.76 MEN1 (0.37) MEN1KMT2AHSD17B10NPC1CYP1A2
SCHEMBL7157444 0.76 MEN1 (0.38) MEN1KMT2AHSD17B10NPC1CYP1A2
SCHEMBL8013857 0.76 LTA4H (0.46) MEN1KMT2AHSD17B10NPC1CYP1A2
SCHEMBL17714046 0.74 KDM4E (0.41) MEN1KMT2AHSD17B10NPC1CYP1A2
SCHEMBL5277507 0.74 KCNH2 (0.50) MEN1KMT2AHSD17B10NPC1CYP1A2
SCHEMBL20837438 0.73 HSD17B10 (0.48) MEN1KMT2AHSD17B10NPC1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060234151-A1 Functional organic thin film, organic thin-film transistor, and methods for producing these SHARP KABUSHIKI KAISHA (JP) 2006-10-19 US claimed
US-7125653-B2 Method of producing conductive or semiconducting structured polymers INFINEON TECHNOLOGIES AG (DE) 2006-10-24 US disclosed
US-20060234151-A1 Functional organic thin film, organic thin-film transistor, and methods for producing these SHARP KABUSHIKI KAISHA (JP) 2006-10-19 US disclosed
US-20030027079-A1 Method of producing conductive or semiconducting structured polymers POLARIS INNOVATIONS LIMITED (IE) 2003-02-06 US disclosed