SCHEMBL5671671

SCHEMBL5671671

CCCCCCCCCCCC(SSC(CCCCCCCCCCC)[Si](OCC)(OCC)OCC)[Si](OCC)(OCC)OCC

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.37
LMNA P02545 1/20 0.34
DNM1 Q05193 2/20 0.33
SMPD1 P17405 3/20 0.32
TSHR P16473 1/20 0.32
THRB P10828 1/20 0.32
ZDHHC7 Q9NXF8 1/20 0.32
GPR84 Q9NQS5 3/20 0.31
FDPS P14324 3/20 0.31
SPHK1 Q9NYA1 1/20 0.31
FFAR1 O14842 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10943677 0.92 OPRM1 (0.34) OPRM1LMNADNM1SMPD1ZDHHC7
SCHEMBL8827101 0.92 OPRM1 (0.34) OPRM1LMNADNM1SMPD1ZDHHC7
SCHEMBL11787635 0.92 OPRM1 (0.34) OPRM1LMNADNM1SMPD1ZDHHC7
SCHEMBL8827105 0.92 OPRM1 (0.34) OPRM1LMNADNM1SMPD1ZDHHC7
SCHEMBL8826404 0.91 OPRM1 (0.33) OPRM1LMNADNM1SMPD1
SCHEMBL8826915 0.91 OPRM1 (0.33) OPRM1LMNADNM1SMPD1
SCHEMBL8827242 0.91 OPRM1 (0.33) OPRM1LMNADNM1SMPD1
SCHEMBL8826969 0.91 OPRM1 (0.33) OPRM1LMNADNM1SMPD1
SCHEMBL504805 0.90 OPRM1 (0.35) OPRM1
SCHEMBL5671676 0.89 OPRM1 (0.34) OPRM1LMNADNM1SMPD1ZDHHC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0995775-B1 Preparation of stach reinforced rubber, vulcanized rubber tire and article of manufacture GOODYEAR TIRE & RUBBER (US) 2004-08-18 EP claimed
EP-0994150-B1 Preparation of reinforced rubber GOODYEAR TIRE & RUBBER (US) 2004-03-24 EP claimed
US-6458871-B2 MIXING A ORGANOSILANE DISULFIDE, A RUBBER AND A REINFORCING FILLER THE GOODYEAR TIRE & RUBBER COMPANY 2002-10-01 US claimed
US-6384127-B2 MIXTURE CONTAINING ORGANOSILANE DISULFIDE COMPOUND THE GOODYEAR TIRE & RUBBER COMPANY 2002-05-07 US claimed
US-20020019473-A1 SILICA REINFORCED RUBBER COMPOSITION AND USE IN TIRES GOODYEAR TIRE & RUBBER COMPANY, THE 2002-02-14 US claimed
US-20010034392-A1 Preparation of reinforced rubber and use in tires THE GOODYEAR TIRE & RUBBER COMPANY 2001-10-25 US claimed
US-6306949-B1 ORGANOSILANE POLYSULFIDE THE GOODYEAR TIRE & RUBBER COMPANY 2001-10-23 US claimed
US-20010031803-A1 Preparation of starch reinforced rubber and use thereof in tires THE GOODYEAR TIRE & RUBBER COMPANY 2001-10-18 US claimed
US-6273163-B1 ORGANOSILICON (DI OR TRI)SULFIDE THE GOODYEAR TIRE & RUBBER COMPANY 2001-08-14 US claimed
US-6218561-B1 REACTING A MERCAPTOALKOXYSILANE WITH A N-ALKYLBIS(BENZOTHIAZOLSULFEN)AMIDE. THE GOODYEAR TIRE & RUBBER COMPANY 2001-04-17 US claimed
EP-0732362-B1 Silica reinforced rubber composition and use in tyres GOODYEAR TIRE & RUBBER (US) 1999-06-02 EP claimed
EP-0845493-A1 Silica reinforced rubber composition and use in tires THE GOODYEAR TIRE & RUBBER COMPANY (US) 1998-06-03 EP claimed
US-5675014-A Process for the preparation of organosilicon disulfide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-10-07 US claimed
US-5663358-A Process for the preparation of organosilicon disulfide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-09-02 US claimed
EP-0785206-A1 Process for the preparation of organosilicon disulfide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-07-23 EP claimed
EP-0785207-A1 Process for the preparation of organosilicon disulfide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-07-23 EP claimed
US-5580919-A ORGANOSILANE DISULFIDE COUPLER THE GOODYEAR TIRE & RUBBER COMPANY (US) 1996-12-03 US claimed
EP-0732362-A1 Silica reinforced rubber composition and use in tyres THE GOODYEAR TIRE & RUBBER COMPANY (US) 1996-09-18 EP claimed
EP-0718302-A1 Process for the preparation of organosilicon disulfide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1996-06-26 EP claimed
US-5440064-A Process for the preparation of organosilicon disulfide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1995-08-08 US claimed