Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 7/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | CETP | P11597 | 8/20 | 0.38 |
| ▸ | PPIA | P62937 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5671027 | 0.76 | LMNA (0.40) | MAOBCETPPPIALMNA | |
| SCHEMBL27901340 | 0.70 | KDM1A (0.59) | KDM1AMAOAMAOBLMNAHPGD | |
| SCHEMBL5671808 | 0.69 | GSK3B (0.47) | MAOBLMNA | |
| SCHEMBL5670482 | 0.68 | MAOB (0.46) | MAOBLMNA | |
| SCHEMBL3606076 | 0.68 | KDM1A (0.56) | KDM1AMAOAMAOBLMNAHPGD | |
| SCHEMBL30674665 | 0.68 | KDM1A (0.56) | KDM1AMAOAMAOBLMNAHPGD | |
| SCHEMBL3920253 | 0.68 | KDM1A (0.59) | KDM1AMAOAMAOB | |
| SCHEMBL30259750 | 0.68 | KDM1A (0.56) | KDM1AMAOAMAOB | |
| SCHEMBL31266300 | 0.67 | KDM1A (0.52) | KDM1AMAOAMAOBLMNAHPGD | |
| SCHEMBL2561377 | 0.67 | KDM1A (0.52) | KDM1AMAOAMAOBLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670446-A2 | METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION | JAPAN TOBACCO INC. (JP) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005030185-A2 | METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION | JAPAN TOBACCO INC. (JP) | 2005-04-07 | — | — | WO | disclosed |