Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | CD4 | P01730 | 2/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 8/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5672936 | 1.00 | BCL2L1 (0.44) | BCL2L1MCL1CD4PTGER3HRH3 | |
| SCHEMBL5672537 | 0.99 | BCL2L1 (0.43) | BCL2L1MCL1CD4PTGER3HRH3 | |
| SCHEMBL5672531 | 0.99 | BCL2L1 (0.43) | BCL2L1MCL1CD4PTGER3HRH3 | |
| SCHEMBL5672196 | 0.86 | BCL2L1 (0.36) | BCL2L1MCL1PTGER3ALOX5AP | |
| SCHEMBL5672192 | 0.86 | BCL2L1 (0.36) | BCL2L1MCL1PTGER3ALOX5AP | |
| SCHEMBL5672195 | 0.86 | BCL2L1 (0.36) | BCL2L1MCL1PTGER3ALOX5AP | |
| SCHEMBL5675467 | 0.86 | HRH3 (0.38) | BCL2L1MCL1PTGER3HRH3 | |
| SCHEMBL5675465 | 0.86 | HRH3 (0.38) | BCL2L1MCL1PTGER3HRH3 | |
| SCHEMBL5675536 | 0.85 | SLC16A3 (0.36) | BCL2L1MCL1PTGER3KCNH2ALOX5AP | |
| SCHEMBL5673774 | 0.85 | PPARG (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1142879-A1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | claimed |
| US-7060721-B1 | Imidazole compounds and medicinal use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2006-06-13 | — | — | US | disclosed |
| EP-1142879-A1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |