Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 15/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5673036 | 1.00 | PPARG (0.41) | PPARGHDAC8PTGDR2 | |
| SCHEMBL5673941 | 0.95 | HDAC8 (0.39) | PPARGHDAC8PTGDR2 | |
| SCHEMBL5673937 | 0.95 | HDAC8 (0.39) | PPARGHDAC8PTGDR2 | |
| SCHEMBL5672940 | 0.94 | PPARG (0.40) | PPARGHDAC8PTGDR2 | |
| SCHEMBL5672937 | 0.94 | PPARG (0.40) | PPARGHDAC8PTGDR2 | |
| SCHEMBL5672164 | 0.93 | HDAC8 (0.41) | PPARGHDAC8PTGDR2 | |
| SCHEMBL5672167 | 0.93 | HDAC8 (0.41) | PPARGHDAC8PTGDR2 | |
| SCHEMBL5675450 | 0.93 | HDAC8 (0.41) | PPARGHDAC8 | |
| SCHEMBL5675446 | 0.93 | HDAC8 (0.41) | PPARGHDAC8 | |
| SCHEMBL6134996 | 0.93 | HDAC8 (0.41) | PPARGHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1142879-A1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | claimed |
| US-7060721-B1 | Imidazole compounds and medicinal use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2006-06-13 | — | — | US | disclosed |
| EP-1142879-A1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |