SCHEMBL5674444

SCHEMBL5674444

N=C(N)c1ccc(NC(=O)NCC(=O)NCCc2ccccc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
F7 P08709 14/20 0.64
F10 P00742 3/20 0.62
F2 P00734 5/20 0.61
HDAC1 Q13547 2/20 0.61
HDAC2 Q92769 2/20 0.61
ST14 Q9Y5Y6 1/20 0.59
NPC1 O15118 1/20 0.55
CNR1 P21554 1/20 0.55
RAB9A P51151 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
CA2 P00918 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4588318 0.84 F7 (0.66) F7F10F2CNR1
SCHEMBL13714617 0.79 F7 (0.65) F7F10F2
SCHEMBL5154948 0.79 ST14 (0.44) F7F2HDAC1HDAC2ST14
SCHEMBL4426386 0.79 F7 (0.64) F7F10F2ST14
SCHEMBL4419447 0.78 F7 (1.00) F7F10F2
SCHEMBL4420144 0.77 F7 (1.00) F7F10F2CNR1
SCHEMBL236558 0.77 F7 (1.00) F7F10F2
SCHEMBL235788 0.76 F7 (1.00) F7F10F2
SCHEMBL13936352 0.76 F7 (1.00) F7F10F2
Hydrochloric Acid SCHEMBL234684 0.76 F7 (0.98) F7F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1656158-A2 LIQUID, AQUEOUS PHARMACEUTICAL COMPOSITION OF FACTOR VII POLYPEPTIDES Novo Nordisk Health Care AG (CH) 2006-05-17 EP claimed
WO-2005016365-A2 LIQUID, AQUEOUS PHARMACEUTICAL COMPOSITION OF FACTOR VII POLYPEPTIDES NOVO NORDISK HEALTH CARE AG (CH) 2005-02-24 WO claimed
EP-1656158-A2 LIQUID, AQUEOUS PHARMACEUTICAL COMPOSITION OF FACTOR VII POLYPEPTIDES Novo Nordisk Health Care AG (CH) 2006-05-17 EP disclosed
WO-2005016365-A2 LIQUID, AQUEOUS PHARMACEUTICAL COMPOSITION OF FACTOR VII POLYPEPTIDES NOVO NORDISK HEALTH CARE AG (CH) 2005-02-24 WO disclosed