Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5182867 | 0.85 | CNR1 (0.50) | CNR1ALDH1A1CA2F2POLB | |
| SCHEMBL5674444 | 0.79 | F7 (0.64) | ST14SMN1; SMN2NPC1RAB9AHDAC1 | |
| SCHEMBL4962106 | 0.78 | RECQL (0.50) | SMN1; SMN2HPGDL3MBTL1POLB | |
| SCHEMBL4961414 | 0.78 | F7 (0.67) | NPC1CNR1F2POLBF7 | |
| SCHEMBL4958063 | 0.77 | RAB9A (0.49) | SMN1; SMN2NPC1RAB9AHPGDL3MBTL1 | |
| SCHEMBL4959775 | 0.77 | F7 (0.66) | F2F7 | |
| SCHEMBL4960599 | 0.77 | F7 (0.45) | ALDH1A1F2F7 | |
| SCHEMBL4960233 | 0.76 | F7 (0.50) | F2F7 | |
| SCHEMBL4960568 | 0.76 | HPGD (0.54) | SMN1; SMN2NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL4958068 | 0.75 | F7 (0.48) | F2F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856091-A1 | COMPOUNDS FOR STABILIZING FACTOR VII POLYPEPTIDE FORMULATIONS | Novo Nordisk Health Care AG (CH) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006089953-A1 | COMPOUNDS FOR STABILIZING FACTOR VII POLYPEPTIDE FORMULATIONS | NOVO NORDISK HEALTH CARE AG (CH) | 2006-08-31 | — | — | WO | disclosed |