Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL28472155 | 0.92 | THRB (0.50) | THRBTSHRALDH1A1POLBAPEX1 | |
| Acetic Acid SCHEMBL8501989 | 0.90 | THRB (0.52) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL29229747 | 0.89 | THRB (0.59) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL6864388 | 0.89 | THRB (0.59) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL14886 | 0.89 | — | — | |
| Ethylene SCHEMBL629900 | 0.87 | THRB (0.57) | THRBTSHRALDH1A1POLBAPEX1 | |
| Ethylene SCHEMBL1950780 | 0.87 | THRB (0.57) | THRBTSHRALDH1A1POLBAPEX1 | |
| Ethylene SCHEMBL2347824 | 0.87 | THRB (0.57) | THRBTSHRALDH1A1POLBAPEX1 | |
| Ethylene SCHEMBL1248384 | 0.87 | THRB (0.57) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL20701421 | 0.87 | THRB (0.57) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014166994-A1 | NANO-MICRODELIVERY SYSTEMS FOR ORAL DELIVERY OF AN ACTIVE INGREDIENT | DANMARKS TEKNISKE UNIVERSITET (DK) | 2014-10-16 | — | — | WO | disclosed |
| US-20060024248-A1 | Composition and method employing membrane structured solid nanoparticles for enhanced delivery of oral care actives | COMBE INCORPORATED (US) | 2006-02-02 | — | — | US | disclosed |