Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | P4HB | P07237 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5675442 | 1.00 | PPARG (0.37) | PPARGHDAC8PLA2G4AKDM4EP4HB | |
| SCHEMBL5672528 | 0.93 | PPARG (0.40) | PPARGHDAC8PLA2G4AKDM4EP4HB | |
| SCHEMBL5672534 | 0.93 | PPARG (0.40) | PPARGHDAC8PLA2G4AKDM4EP4HB | |
| SCHEMBL5675450 | 0.89 | HDAC8 (0.41) | PPARGHDAC8 | |
| SCHEMBL5675446 | 0.89 | HDAC8 (0.41) | PPARGHDAC8 | |
| SCHEMBL6134996 | 0.89 | HDAC8 (0.41) | PPARGHDAC8 | |
| SCHEMBL5673779 | 0.84 | PPARG (0.38) | PPARG | |
| SCHEMBL5673778 | 0.84 | PPARG (0.38) | PPARG | |
| SCHEMBL27485194 | 0.83 | KDM4E (0.38) | PLA2G4AKDM4EP4HBNPSR1 | |
| SCHEMBL5673036 | 0.82 | PPARG (0.41) | PPARGHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060721-B1 | Imidazole compounds and medicinal use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2006-06-13 | — | — | US | disclosed |