Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GHSR | Q92847 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5675808 | 0.92 | ALDH1A1 (0.45) | BRD4ADCY8ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL5674768 | 0.91 | BRD4 (0.41) | BRD4ADCY8ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL5675722 | 0.89 | BRD4 (0.43) | BRD4ADCY8ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL5676014 | 0.87 | BRD4 (0.48) | BRD4ADCY8ALDH1A1L3MBTL1MAPT | |
| SCHEMBL5675743 | 0.85 | ALDH1A1 (0.47) | BRD4ADCY8ALDH1A1TDP1GHSR | |
| SCHEMBL5674361 | 0.81 | KMT2A (0.48) | BRD4ADCY8ALDH1A1L3MBTL1MAPT | |
| SCHEMBL5677869 | 0.80 | KMT2A (0.43) | BRD4ADCY8ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL5678507 | 0.80 | BRD4 (0.45) | BRD4ADCY8ALDH1A1TDP1HSD17B10 | |
| SCHEMBL5674253 | 0.78 | BRD4 (0.48) | BRD4ADCY8ALDH1A1 | |
| SCHEMBL5678176 | 0.78 | BRD4 (0.40) | BRD4ADCY8ALDH1A1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7119086-B2 | Phenylsulfonyl-1,3-dihydro-2h-indole-2-one derivatives, their preparation and their therapeutic use | SANOFI-AVENTIS (FR) | 2006-10-10 | — | — | US | disclosed |
| US-20040180878-A1 | Phenylsulfonyl-1,3-dihydro-2h-indole-2-one derivatives, their preparation and their therapeutic use | SANOFI-AVENTIS (FR) | 2004-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040180878-A1 | Phenylsulfonyl-1,3-dihydro-2h-indole-2-one derivatives, their preparation and their therapeutic use | AVPR2, AVPR1A, AVPR1B | BRD4 2751/4885ADCY8 1986/4885ALDH1A1 3049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.