SCHEMBL5675835

SCHEMBL5675835

Cc1cc(OCCC=O)cc(OS(=O)(=O)c2cccc(C)c2)c1

nearest known ligand 0.68

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F2 P00734 20/20 0.68
CTRC Q99895 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5676091 0.89 F2 (0.56) F2CTRC
SCHEMBL5673602 0.89 F2 (0.56) F2CTRC
SCHEMBL5674462 0.89 F2 (0.56) F2CTRC
SCHEMBL5675983 0.86 F2 (0.53) F2
SCHEMBL14878155 0.86 F2 (0.62) F2CTRC
SCHEMBL5673584 0.84 F2 (0.63) F2CTRC
SCHEMBL5674320 0.83 F2 (0.70) F2CTRC
SCHEMBL5675805 0.80 F2 (0.68) F2CTRC
SCHEMBL5673399 0.80 F2 (0.48) F2CTRC
SCHEMBL5672977 0.79 F2 (0.70) F2CTRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0906091-B1 AMIDINOHYDRAZONES AS PROTEASE INHIBITORS ORTHO MCNEIL PHARM INC (US) 2006-10-04 EP disclosed
EP-0906091-A4 AMIDINOHYDRAZONES AS PROTEASE INHIBITORS DIMENSIONAL PHARM INC (US) 2004-07-21 EP disclosed
EP-0906091-A1 AMIDINOHYDRAZONES AS PROTEASE INHIBITORS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 1999-04-07 EP disclosed
US-5891909-A Amidinohydrazones as protease inhibitors 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 1999-04-06 US disclosed
WO-1997036580-A1 AMIDINOHYDRAZONES AS PROTEASE INHIBITORS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 1997-10-09 WO disclosed