Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL617245 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL27393748 | 0.76 | — | — | |
| Fluoride Ion SCHEMBL1131207 | 0.75 | — | — | |
| Bromide SCHEMBL7878867 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL6332594 | 0.74 | — | — | |
| SCHEMBL8163375 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL618097 | 0.73 | TSHR (0.31) | — | |
| Hydrochloric Acid SCHEMBL8852948 | 0.71 | — | — | |
| SCHEMBL6812826 | 0.71 | — | — | |
| SCHEMBL8466723 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814574-A | ZIRCONIUM METALLOCENE POLYMERIZATION CATALYSTS; NARROW MOLECULAR WEIGHT DISTRIBUTION | BP CHEMICALS LIMITED (GB) | 1998-09-29 | — | — | US | claimed |
| EP-1390374-B1 | SUPPORTED POLYMERIZATION CATALYST USING A CATALYST PRECUSOR HAVING FUNCTIONAL GROUP AND SURFACE MODIFIED CARRIER AND OLEFIN POLYMERIZATION USING THE SAME | LG CHEMICAL LTD (KR) | 2006-03-01 | — | — | EP | disclosed |
| US-6908877-B2 | Supported polymerization catalyst using a catalyst precursor having functional group and surface modified carrier and olefin polymerization using the same | LG CHEM. LTD. (KR) | 2005-06-21 | — | — | US | disclosed |
| EP-1390374-A1 | SUPPORTED POLYMERIZATION CATALYST USING A CATALYST PRECUSOR HAVING FUNCTIONAL GROUP AND SURFACE MODIFIED CARRIER AND OLEFIN POLYMERIZATION USING THE SAME | LG Chem, Ltd. (KR) | 2004-02-25 | — | — | EP | disclosed |
| US-20030166455-A1 | Supported polymerization catalyst using a catalyst precursor having functional group and surface modified carrier and olefin polymerization using the same | LG CHEM, LTD. (KR) | 2003-09-04 | — | — | US | disclosed |
| WO-2002094841-A1 | SUPPORTED POLYMERIZATION CATALYST USING A CATALYST PRECUSOR HAVING FUNCTIONAL GROUP AND SURFACE MODIFIED CARRIER AND OLEFIN POLYMERIZATION USING THE SAME | LG CHEM, LTD. (KR) | 2002-11-28 | — | — | WO | disclosed |