Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800469 | 0.81 | — | — | |
| SCHEMBL6386792 | 0.81 | — | — | |
| SCHEMBL23612789 | 0.79 | POLB (0.36) | SMN1; SMN2 | |
| SCHEMBL2824552 | 0.77 | BCHE (0.36) | EPHX1KDM4CSMN1; SMN2HSD17B10 | |
| SCHEMBL19642846 | 0.75 | ALDH1A1 (0.48) | EPHX1SMN1; SMN2 | |
| SCHEMBL31317634 | 0.74 | CNR1 (0.40) | EPHX1KDM4CSMN1; SMN2HSD17B10 | |
| SCHEMBL8076135 | 0.74 | — | — | |
| SCHEMBL8908479 | 0.74 | TDP1 (0.48) | EPHX1 | |
| SCHEMBL20734766 | 0.72 | RECQL (0.32) | — | |
| SCHEMBL4028377 | 0.72 | PHF8 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497268-A4 | NITRIC OXIDE DONORS, COMPOSITIONS AND METHODS OF USE | NITROMED INC (US) | 2006-01-18 | — | — | EP | disclosed |
| EP-1497268-A2 | NITRIC OXIDE DONORS, COMPOSITIONS AND METHODS OF USE | Nitromed, Inc. (US) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003086282-A2 | NITRIC OXIDE DONORS, COMPOSITIONS AND METHODS OF USE | NITROMED, INC. (US) | 2003-10-23 | — | — | WO | disclosed |