Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9238358 | 0.95 | TDP1 (0.45) | KMT2AMEN1TDP1KDM4EPOLB | |
| SCHEMBL5682343 | 0.84 | SMN1; SMN2 (0.44) | KMT2AMEN1L3MBTL1OPRM1ALDH1A1 | |
| SCHEMBL28427045 | 0.76 | SMN1; SMN2 (0.46) | KMT2ATDP1KDM4EPOLBTHRB | |
| SCHEMBL10631054 | 0.76 | MEN1 (0.54) | KMT2AMEN1POLBL3MBTL1ALDH1A1 | |
| SCHEMBL15601014 | 0.75 | KMT2A (0.52) | KMT2AMEN1KDM4EPOLBL3MBTL1 | |
| SCHEMBL522136 | 0.74 | KMT2A (0.59) | KMT2ATDP1KDM4EPOLBTHRB | |
| SCHEMBL10626036 | 0.73 | MEN1 (0.56) | KMT2AMEN1POLBL3MBTL1ALDH1A1 | |
| SCHEMBL5678146 | 0.72 | MEN1 (0.44) | KMT2AMEN1POLBL3MBTL1OPRM1 | |
| SCHEMBL5682238 | 0.72 | SMN1; SMN2 (0.51) | KMT2AMEN1KDM4EOPRM1ALDH1A1 | |
| SCHEMBL2706971 | 0.71 | TDP1 (0.51) | KMT2AMEN1TDP1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227085-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE NAPHTHALENE DERIVATIVE AND OPTICAL RESOLVER THEREFOR | TAKEDA PHARMACEUTICAL (JP) | 2006-03-15 | — | — | EP | disclosed |
| US-6800778-B1 | OPTICALLY ACTIVE CYCLIC PHOSPHORUS COMPOUND USED AS REAGENT FOR OPTICAL RESOLUTION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2004-10-05 | — | — | US | disclosed |
| EP-1227085-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE NAPHTHALENE DERIVATIVE AND OPTICAL RESOLVER THEREFOR | Takeda Chemical Industries, Ltd. (JP) | 2002-07-31 | — | — | EP | disclosed |