Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15565974 | 0.80 | CETP (0.47) | ALDH1A1KDM4EL3MBTL1ADORA1LMNA | |
| SCHEMBL123585 | 0.77 | L3MBTL1 (0.42) | ALDH1A1L3MBTL1ADORA1LMNASMN1; SMN2 | |
| SCHEMBL29951599 | 0.75 | L3MBTL1 (0.41) | ALDH1A1KDM4EL3MBTL1ADORA1LMNA | |
| SCHEMBL247107 | 0.75 | L3MBTL1 (0.41) | ALDH1A1KDM4EL3MBTL1ADORA1LMNA | |
| SCHEMBL29950915 | 0.75 | L3MBTL1 (0.41) | ALDH1A1KDM4EL3MBTL1ADORA1LMNA | |
| SCHEMBL2209190 | 0.75 | L3MBTL1 (0.41) | ALDH1A1KDM4EL3MBTL1ADORA1LMNA | |
| SCHEMBL14984329 | 0.75 | BRD4 (0.43) | ALDH1A1KDM4EL3MBTL1ADORA1LMNA | |
| SCHEMBL123133 | 0.74 | L3MBTL1 (0.36) | ALDH1A1KDM4EL3MBTL1GAAADORA1 | |
| SCHEMBL16790819 | 0.73 | L3MBTL1 (0.39) | ALDH1A1KDM4EL3MBTL1ADORA1LMNA | |
| SCHEMBL5126193 | 0.73 | ADORA1 (0.47) | ALDH1A1KDM4EADORA1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988045-B1 | PEPTIDE NUCLEIC ACID MONOMERS AND OLIGOMERS | NIELSEN PETER EIGIL (DK) | 2006-02-08 | — | — | EP | disclosed |
| US-6632919-B1 | Bind Watson-Crick base pairs in a double helix; specific for thymidine | Nielsen, Peter (DK) | 2003-10-14 | — | — | US | disclosed |
| US-6617422-B1 | Of given formula; stronger binding and greater specificity than oligonucleotides; useful as probes in cloning, blotting procedures, and in applications such as fluorescence in situ hybridization; can use to detect point mutations | Nielsen, Peter (DK) | 2003-09-09 | — | — | US | disclosed |
| EP-0988045-A4 | PEPTIDE NUCLEIC ACID MONOMERS AND OLIGOMERS | NIELSEN PETER EIGIL (DK) | 2002-07-24 | — | — | EP | disclosed |
| EP-0988045-A1 | PEPTIDE NUCLEIC ACID MONOMERS AND OLIGOMERS | NIELSEN, Peter Eigil (DK) | 2000-03-29 | — | — | EP | disclosed |
| WO-1998052595-A1 | PEPTIDE NUCLEIC ACID MONOMERS AND OLIGOMERS | ISIS PHARMACEUTICALS, INC. (US) | 1998-11-26 | — | — | WO | disclosed |