SCHEMBL5679303

SCHEMBL5679303

COc1ccc(COS(=O)(=O)C(F)(F)F)cc1

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.61
IDO1 P14902 2/20 0.47
AGXT P21549 2/20 0.47
PTPRZ1 P23471 1/20 0.46
NPC1 O15118 1/20 0.45
POLB P06746 1/20 0.45
RAB9A P51151 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
HTT P42858 1/20 0.45
APLNR P35414 1/20 0.45
APP P05067 3/20 0.44
KMT2A Q03164 1/20 0.44
CA1 P00915 3/20 0.43
LTA4H P09960 1/20 0.43
FFAR1 O14842 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL28500084 0.98 CA2 (0.59) CA2IDO1AGXTPTPRZ1NPC1
SCHEMBL5677195 0.82 CA2 (0.65) CA2AGXTPTPRZ1NPC1RAB9A
SCHEMBL16755999 0.82 CA2 (0.69) CA2IDO1AGXTPTPRZ1KMT2A
SCHEMBL20478039 0.81 IDO1 (0.53) CA2IDO1AGXT
SCHEMBL17708496 0.81 CA2 (0.52) CA2SMN1; SMN2HTTCA1
Ammonia Solution, Strong SCHEMBL28355326 0.81 CA2 (0.63) CA2AGXTPTPRZ1NPC1RAB9A
SCHEMBL778365 0.80 CA2 (0.67) CA2IDO1AGXTPTPRZ1APP
SCHEMBL8816369 0.80 CA2 (0.58) CA2PTPRZ1KMT2ACA1
Ammonia Solution, Strong SCHEMBL28351570 0.80 IDO1 (0.51) CA2IDO1AGXT
SCHEMBL6212120 0.80 IDO1 (0.55) CA2IDO1AGXTNPC1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112321469-B Synthetic method of dibenzyl sulfide 成都理工大学 2022-07-12 CN claimed
CN-110683975-B Synthesis method of dialkyl amino alkyl dithioformate 成都理工大学 2021-04-09 CN claimed
CN-112321469-A Synthetic method of dibenzyl sulfide 成都理工大学 2021-02-05 CN claimed
CN-110683975-A Synthesis method of dialkyl amino alkyl dithioformate 成都理工大学 2020-01-14 CN claimed
EP-3004120-B1 SPIRO-1,1'-BIINDANE-7,7-BISPHOSPHINE OXIDES AS HIGHLY ACTIVE SUPPORTING LIGANDS FOR PALLADIUM-CATALYZED ASYMMETRIC HECK REACTION UNIV NANYANG TECH (SG) 2018-08-29 EP claimed
EP-3004120-A1 SPIRO-1,1'-BIINDANE-7,7-BISPHOSPHINE OXIDES AS HIGHLY ACTIVE SUPPORTING LIGANDS FOR PALLADIUM-CATALYZED ASYMMETRIC HECK REACTION Nanyang Technological University (SG) 2016-04-13 EP claimed
WO-2014196930-A1 SPIRO-1,1'-BIINDANE-7,7-BISPHOSPHINE OXIDES AS HIGHLY ACTIVE SUPPORTING LIGANDS FOR PALLADIUM-CATALYZED ASYMMETRIC HECK REACTION NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2014-12-11 WO claimed
US-7001973-B2 Catalyst and process for preparing low-viscosity and color-reduced polyisocyanates containing isocyanurate groups DEGUSSA AG (DE) 2006-02-21 US claimed
CN-113423427-A IRAK degrading agents and uses thereof 凯麦拉医疗公司 2021-09-21 CN disclosed
CN-101506134-B Process for producing benzaldehyde compound UBE INDUSTRIES 2012-12-05 CN disclosed
CN-101506134-A Process for producing benzaldehyde compound UBE INDUSTRIES (JP) 2009-08-12 CN disclosed
US-7001973-B2 Catalyst and process for preparing low-viscosity and color-reduced polyisocyanates containing isocyanurate groups DEGUSSA AG (DE) 2006-02-21 US disclosed
EP-1229016-B1 Catalyst and process for the preparation of isocyanate groups containing polyisocyanates with low viscosity and reduced colour DEGUSSA (DE) 2006-01-11 EP disclosed
US-20030187178-A1 Catalyst and process for preparing low-viscosity and color-reduced polyisocyanates containing isocyanurate groups DEGUSSA AG (DE) 2003-10-02 US disclosed
US-20020120089-A1 Catalyst and process for preparing low-viscosity and color-reduced polyisocyanates containing isocyanurate groups DEGUSSA AG (DE) 2002-08-29 US disclosed
EP-1229016-A2 Catalyst and process for the preparation of isocyanate groups containing polyisocyanates with low viscosity and reduced colour Degussa AG (DE) 2002-08-07 EP disclosed
US-4962146-A 3-O-glycosyl 16-membered macrolide antibacterials and related derivatives SCHERING CORPORATION (US) 1990-10-09 US disclosed
EP-0362267-A1 3-O-GLYCOSYL 16-MEMBERED MACROLIDE ANTIBACTERIALS AND RELATED DERIVATIVES SCHERING CORPORATION (US) 1990-04-11 EP disclosed
EP-0290203-A1 3-O-glycosyl 16-membered macrolide antibacterials and related derivatives SCHERING CORPORATION (US) 1988-11-09 EP disclosed
WO-1988008426-A1 3-O-GLYCOSYL 16-MEMBERED MACROLIDE ANTIBACTERIALS AND RELATED DERIVATIVES SCHERING CORPORATION (US) 1988-11-03 WO disclosed