Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 4/20 | 0.63 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18725542 | 1.00 | ANPEP (0.63) | ANPEPERAP1ERAP2EPHX1LTA4H | |
| Hydrochloric Acid SCHEMBL5681274 | 0.98 | ANPEP (0.61) | ANPEPERAP1ERAP2EPHX1LTA4H | |
| Hydrochloric Acid SCHEMBL5679099 | 0.98 | ANPEP (0.61) | ANPEPERAP1ERAP2EPHX1LTA4H | |
| Hydrochloric Acid SCHEMBL7613449 | 0.98 | ANPEP (0.61) | ANPEPERAP1ERAP2EPHX1LTA4H | |
| SCHEMBL5681048 | 0.88 | ANPEP (0.59) | ANPEPEPHX1HTR2AIDO1ENPEP | |
| SCHEMBL5683047 | 0.88 | ANPEP (0.59) | ANPEPEPHX1HTR2AIDO1ENPEP | |
| SCHEMBL4895850 | 0.86 | EPHX1 (0.56) | ANPEPERAP1ERAP2EPHX1CYP2A6 | |
| Hydrochloric Acid SCHEMBL7620586 | 0.86 | ANPEP (0.57) | ANPEPEPHX1HTR2AENPEP | |
| Hydrochloric Acid SCHEMBL5683083 | 0.86 | ANPEP (0.57) | ANPEPEPHX1HTR2AENPEP | |
| Hydrochloric Acid SCHEMBL5681070 | 0.86 | ANPEP (0.57) | ANPEPEPHX1HTR2AENPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144348-B1 | LTA 4 HYDROLASE INHIBITORS | BIOPROJET SOC CIV (FR) | 2006-02-08 | — | — | EP | claimed |
| EP-1144348-A3 | LTA 4? HYDROLASE INHIBITORS | BIOPROJET (FR) | 2002-09-11 | — | — | EP | claimed |
| EP-1144348-A2 | LTA 4? HYDROLASE INHIBITORS | BIOPROJET (FR) | 2001-10-17 | — | — | EP | claimed |
| WO-2000017133-A2 | LTA4 HYDROLASE INHIBITORS | BIOPROJET (FR) | 2000-03-30 | — | — | WO | claimed |
| EP-1144348-B1 | LTA 4 HYDROLASE INHIBITORS | BIOPROJET SOC CIV (FR) | 2006-02-08 | — | — | EP | disclosed |
| EP-1144348-A3 | LTA 4? HYDROLASE INHIBITORS | BIOPROJET (FR) | 2002-09-11 | — | — | EP | disclosed |
| EP-1144348-A2 | LTA 4? HYDROLASE INHIBITORS | BIOPROJET (FR) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000017133-A2 | LTA4 HYDROLASE INHIBITORS | BIOPROJET (FR) | 2000-03-30 | — | — | WO | disclosed |