Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 4/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7608939 | 0.75 | ERN1 (0.58) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL10899140 | 0.74 | ALDH1A1 (0.50) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL19854388 | 0.73 | ERN1 (0.58) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL5515488 | 0.73 | ERN1 (0.51) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL19330829 | 0.73 | ALDH1A1 (0.47) | ALDH1A1ERN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4889755 | 0.73 | ALDH1A1 (0.49) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL1679164 | 0.72 | ERN1 (0.42) | ALDH1A1ERN1CYP2A6CYP1A2CYP2C9 | |
| SCHEMBL5155542 | 0.72 | ALDH1A1 (0.41) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL3677399 | 0.71 | ALDH1A1 (0.59) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL4898021 | 0.70 | ALDH1A1 (0.56) | ALDH1A1ERN1CYP2A6CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620392-A2 | HYDROXY-BIPHENYL-CARBALDEHYDE OXIME DERIVATIVES AND THEIR USE AS ESTROGENIC AGENTS | Wyeth (US) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004099122-A2 | HYDROXY-BIPHENYL-CARBALDEHYDE OXIME DERIVATIVES AND THEIR USE AS ESTROGENIC AGENTS | WYETH (US) | 2004-11-18 | — | — | WO | disclosed |