Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
| ▸ | GABRE | P78334 | 1/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.34 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.34 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5924180 | 0.79 | CSNK2A2 (0.42) | CSNK2A2CSNK2BCSNK2A1FABP6 | |
| SCHEMBL20479501 | 0.73 | CSNK2A2 (0.35) | CSNK2A2CSNK2BCSNK2A1FABP6 | |
| SCHEMBL20298117 | 0.73 | CSNK2A2 (0.46) | CSNK2A2CSNK2BCSNK2A1FABP6 | |
| SCHEMBL1193115 | 0.72 | PARP1 (0.54) | PARP1 | |
| SCHEMBL1193117 | 0.69 | MEN1 (0.42) | BRPF1SMN1; SMN2BRD4PARP1FABP6 | |
| SCHEMBL1202591 | 0.68 | ALDH1A1 (0.46) | — | |
| SCHEMBL31523087 | 0.68 | CSNK2A2 (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL27447547 | 0.68 | NOTUM (0.39) | SMN1; SMN2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL7049510 | 0.67 | POLB (0.48) | BRPF1SMN1; SMN2GABRPGABRDGABRA1 | |
| SCHEMBL31523499 | 0.67 | CSNK2A2 (0.40) | CSNK2A2CSNK2BCSNK2A1XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620413-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004098494-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2004-11-18 | — | — | WO | disclosed |