⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18898801 | 0.82 | — | — | |
| SCHEMBL16373416 | 0.78 | — | — | |
| SCHEMBL13877116 | 0.76 | — | — | |
| SCHEMBL10667910 | 0.76 | TSHR (0.44) | — | |
| SCHEMBL6600699 | 0.76 | NOS1 (0.33) | — | |
| SCHEMBL4736148 | 0.73 | — | — | |
| SCHEMBL4736150 | 0.73 | — | — | |
| SCHEMBL1171183 | 0.73 | MYC (0.30) | — | |
| SCHEMBL11450880 | 0.73 | NOS1 (0.33) | — | |
| SCHEMBL974938 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276653-A1 | Process for producing quinoline compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1614682-A1 | PROCESS FOR PRODUCING QUINOLINE COMPOUND | Nissan Chemical Industries, Ltd. (JP) | 2006-01-11 | — | — | EP | disclosed |
| US-5132312-A | 3-hydroxy-3-methylglutarylcoenzyme A reductase inhibitors as anticholesterol agents | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1992-07-21 | — | — | US | disclosed |
| WO-1991013616-A1 | NOVEL HMG-CoA REDUCTASE INHIBITORS | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1991-09-19 | — | — | WO | disclosed |
| EP-0403487-A4 | NOVEL HMG-COA REDUCTASE INHIBITORS | — | 1991-06-05 | — | — | EP | disclosed |
| WO-1991004736-A1 | SUBSTITUTED CYCLOHEXENE DERIVATIVES AS HMG-CoA REDUCTASE INHIBITORS | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1991-04-18 | — | — | WO | disclosed |
| US-5001144-A | Substituted cyclohexene derivatives as HMG-CoA reductase inhibitors | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1991-03-19 | — | — | US | disclosed |
| US-4996234-A | Anticholesterol agents | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1991-02-26 | — | — | US | disclosed |
| US-4994494-A | HMG-COA reductase inhibitors | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0403487-A1 | NOVEL HMG-CoA REDUCTASE INHIBITORS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1990-12-27 | — | — | EP | disclosed |
| US-4322563-A | Substituted biphenyl-2-carboxaldehydes | MERCK & CO., INC. (US) | 1982-03-30 | — | — | US | disclosed |
| US-4308378-A | Cis/trans isomerization of 6-(substituted-aryl-ethenyl)-3,4,5,6-tetrahydro-4-hydroxy-2H-pyran-2-ones | MERCK & CO., INC. (US) | 1981-12-29 | — | — | US | disclosed |
| EP-0038061-A1 | Substituted biphenyl-2-carboxaldehydes and a process for preparing them | MERCK & CO. INC. (US) | 1981-10-21 | — | — | EP | disclosed |
| EP-0024348-A1 | Substituted 6-Phenethyl-and phenylethenyl-3,4,5,6-tetrahydro-4-hydroxytetraydropyran-2-ones in the4-R trans stereoisomeric forms and the corresponding dihydroxy acids, process for preparing and pharmaceutical composition comprising them | MERCK & CO. INC. (US) | 1981-03-04 | — | — | EP | disclosed |
| US-4226892-A | Flavoring with cycloaliphatic unsaturated ketones | FIRMENICH SA (CH) | 1980-10-07 | — | — | US | disclosed |
| US-4187863-A | Cycloaliphatic unsaturated ketones as odor and taste modifying agents in tobacco products | FIRMENICH SA (CH) | 1980-02-12 | — | — | US | disclosed |
| US-4102888-A | VASODILATORS, ANTITHROMBITIC | MERCK & CO., INC. (US) | 1978-07-25 | — | — | US | disclosed |
| US-4059587-A | 8-AZA-9-OXO-11-THIA-PROSTANOIC ACID DERIVATIVES; VASODILATORS, ANTICLOTTING, REGULATORS OF IMMUNE RESPONSE | MERCK & CO., INC. (US) | 1977-11-22 | — | — | US | disclosed |
| US-3975310-A | PERFUME | FIRMENICH S.A. (CH) | 1976-08-17 | — | — | US | disclosed |
| US-3931326-A | FLAVOR, TASTE, ODOR, PERFUMES | FIRMENICH SA (CH) | 1976-01-06 | — | — | US | disclosed |