SCHEMBL5680185

SCHEMBL5680185

CCCCCCCCCCCCCCCCCCCC1NCCN1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
GBA1 P04062 7/20 0.42
EPHX1 P07099 1/20 0.41
SPHK1 Q9NYA1 2/20 0.41
GUSB P08236 1/20 0.41
TSHR P16473 1/20 0.40
THRB P10828 1/20 0.40
ALOX5 P09917 1/20 0.39
GLB1 P16278 1/20 0.38
GBA2 Q9HCG7 1/20 0.38
S1PR1 P21453 1/20 0.37
S1PR3 Q99500 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27260431 1.00 ALDH1A1 (0.44) ALDH1A1GBA1EPHX1SPHK1GUSB
SCHEMBL5675532 1.00 ALDH1A1 (0.44) ALDH1A1GBA1EPHX1SPHK1GUSB
SCHEMBL27992616 1.00 ALDH1A1 (0.44) ALDH1A1GBA1EPHX1SPHK1GUSB
SCHEMBL28815780 1.00 ALDH1A1 (0.44) ALDH1A1GBA1EPHX1SPHK1GUSB
SCHEMBL5677084 1.00 ALDH1A1 (0.44) ALDH1A1GBA1EPHX1SPHK1GUSB
SCHEMBL4340747 1.00 ALDH1A1 (0.44) ALDH1A1GBA1EPHX1SPHK1GUSB
SCHEMBL28969103 1.00 ALDH1A1 (0.44) ALDH1A1GBA1EPHX1SPHK1GUSB
SCHEMBL5675531 1.00 ALDH1A1 (0.44) ALDH1A1GBA1EPHX1SPHK1GUSB
SCHEMBL21585703 1.00 ALDH1A1 (0.44) ALDH1A1GBA1EPHX1SPHK1GUSB
SCHEMBL27992831 1.00 ALDH1A1 (0.44) ALDH1A1GBA1EPHX1SPHK1GUSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7094901-B2 Expanded anionic compounds comprising hydroxyl or quiescent reactive functionality and catalyst activators therefrom DOW GLOBAL MICHIGAN TECHNOLOGIES INC. (US) 2006-08-22 US disclosed
EP-1228109-B1 SUPPORTED CATALYST COMPRISING EXPANDED ANIONS DOW GLOBAL TECHNOLOGIES INC (US) 2006-02-01 EP disclosed
US-20050009688-A1 Expanded anionic compounds comprising hydroxyl or quiescent reactive functionality and catalyst activators therefrom BABB DAVID A (US) 2005-01-13 US disclosed
US-20040077491-A1 Expanded anionic compounds comprising hydroxyl or quiescent reactive functionality and catalyst activators therefrom THE DOW CHEMICAL COMPANY (US) 2004-04-22 US disclosed
US-6716786-B1 LEWIS ACIDS AND BASES THE DOW CHEMICAL COMPANY 2004-04-06 US disclosed
US-6627573-B2 Useful as a cocatalyst for addition coordination polymerization comprising an anion containing at least two Lewis basic sites which are coordinated to Lewis acids, and further containing a hydroxyl group for support attachment THE DOW CHEMICAL COMPANY 2003-09-30 US disclosed
CN-1120168-C Catalyst activators comprising expanded anions DOW WORLDWIDE TECHNOLOGY INC (US) 2003-09-03 CN disclosed
EP-1056752-B1 Catalyst activators comprising expanded anions DOW GLOBAL TECHNOLOGIES INC (US) 2003-06-25 EP disclosed
US-6462156-B2 AS POLYMERIZATION CATALYST FOR PRODUCING OLEFIN POLYMERS THE DOW CHEMICAL COMPANY 2002-10-08 US disclosed
US-20020132729-A1 Catalyst activators comprising expanded anions LAPOINTE ROBERT E (US) 2002-09-19 US disclosed
EP-1228109-A1 SUPPORTED CATALYST COMPRISING EXPANDED ANIONS THE DOW CHEMICAL COMPANY (US) 2002-08-07 EP disclosed
US-6395671-B2 ANION CONTAINING TWO LEWIS BASIC SITES WHICH ARE COORDINATED TO LEWIS ACIDS; FOR OLEFIN POLYMERIZATION THE DOW CHEMICAL COMPANY 2002-05-28 US disclosed
US-20020032120-A1 Expanded anionic compounds comprising hydroxyl or quiescent reactive functionality and catalyst activators therefrom DOW CHEMICAL COMPANY, THE 2002-03-14 US disclosed
WO-2002008303-A1 EXPANDED ANIONIC COMPOUNDS COMPRISING HYDROXYL OR QUIESCENT REACTIVE FUNCTIONALITY AND CATALYST ACTIVATORS THEREFROM THE DOW CHEMICAL COMPANY (US) 2002-01-31 WO disclosed
US-20010027161-A1 Catalyst activators comprising expanded anions THE DOW CHEMICAL COMPANY 2001-10-04 US disclosed
WO-2001023442-A1 SUPPORTED CATALYST COMPRISING EXPANDED ANIONS THE DOW CHEMICAL COMPANY (US) 2001-04-05 WO disclosed
CN-1290267-A Catalyst activators comprising expanded anions DOW CHEMICAL CO (US) 2001-04-04 CN disclosed
EP-1056752-A1 CATALYST ACTIVATORS COMPRISING EXPANDED ANIONS THE DOW CHEMICAL COMPANY (US) 2000-12-06 EP disclosed
WO-1999042467-A1 CATALYST ACTIVATORS COMPRISING EXPANDED ANIONS THE DOW CHEMICAL COMPANY (US) 1999-08-26 WO disclosed