Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3106392 | 0.91 | IDO1 (0.64) | NOS1NPC1RAB9AIDO1TDP1 | |
| SCHEMBL1833158 | 0.89 | CYP1A2 (0.53) | NOS1NPC1RAB9AIDO1TDP1 | |
| SCHEMBL16047247 | 0.87 | KMT2A (0.52) | TDP1KMT2ASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL31131464 | 0.83 | KMT2A (0.49) | TDP1HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL7909243 | 0.83 | KMT2A (0.49) | TDP1KMT2ASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL10952894 | 0.81 | GSK3B (0.50) | TDP1KMT2ASMN1; SMN2MAPK1ALDH1A1 | |
| Tibenzate SCHEMBL2110094 | 0.81 | IDO1 (0.52) | NOS1IDO1TDP1HDAC1HDAC3 | |
| SCHEMBL6830395 | 0.81 | KMT2A (0.47) | TDP1KMT2ASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL6549496 | 0.79 | IDO1 (0.53) | IDO1TDP1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL8423263 | 0.79 | KMT2A (0.46) | TDP1HDAC1HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102492105-B | Two-waveband dumbbell-shaped macromolecular ultraviolet absorbers and preparation method thereof | UNIV NANTONG | 2014-04-09 | — | — | CN | claimed |
| CN-102492105-A | Two-waveband dumbbell-shaped macromolecular ultraviolet absorbers and a preparation method thereof | UNIV NANTONG | 2012-06-13 | — | — | CN | claimed |
| CN-102492105-B | Two-waveband dumbbell-shaped macromolecular ultraviolet absorbers and preparation method thereof | UNIV NANTONG | 2014-04-09 | — | — | CN | disclosed |
| CN-102492105-A | Two-waveband dumbbell-shaped macromolecular ultraviolet absorbers and a preparation method thereof | UNIV NANTONG | 2012-06-13 | — | — | CN | disclosed |
| US-7019033-B2 | 2-(4-bromo or 4-iodo phenylamino) benzoic acid derivatives | WARNER-LAMBERT COMPANY (US) | 2006-03-28 | — | — | US | disclosed |