SCHEMBL5680378

SCHEMBL5680378

Cc1cccc(NF)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitrogen SCHEMBL28285955 0.95 MAPT (0.59)
Hydrochloric Acid SCHEMBL4587802 0.79 MAPT (0.57)
SCHEMBL29650380 0.79 NPSR1 (0.86)
SCHEMBL1009206 0.79 NPSR1 (0.86)
SCHEMBL6694995 0.79 GAA (0.65)
SCHEMBL8373327 0.78 MAPT (1.00)
SCHEMBL29697291 0.77
Water SCHEMBL8601146 0.77 NPSR1 (0.82)
SCHEMBL9158496 0.77 NPSR1 (0.82)
SCHEMBL306337 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109593380-A A kind of dye composition and preparation method thereof, application 北京泛博清洁技术研究院有限公司 2019-04-09 CN claimed
CN-103570754-B The preparation method of N (4 (base of 3 amino 1H indazoles 4) phenyl) N ' (aminomethyl phenyl of 2 fluorine 5) ureas and its intermediate 上海创诺医药集团有限公司 2018-01-26 CN claimed
CN-107074878-A 2, 3-dihydro-thiazolo [3,2-a ] pyridin-5-one derivatives, intermediates thereof and their use as antibacterial agents 快尔生物技术公司 2017-08-18 CN claimed
CN-103380137-B The nitrogen-containing heterocycle compound of a kind of N ortho position acyl substituted and contracting amine thereof close the preparation method of iron (II) title complex CHINA PETROLEUM & CHEMICAL CORP. (CN) 2016-02-10 CN claimed
CN-102791712-B Pyrazolopyrimidine Derivatives KYOWA HAKKO KIRIN CO LTD 2015-07-01 CN claimed
CN-102964388-B Preparation method of benzoyl-substituted 1,10-phenanthroline complex and catalytic application in ethylene oligomerization CHINA PETROLEUM & CHEMICAL 2015-03-11 CN claimed
CN-102485733-B Preparation of acetyl-substituted-1,10-phenanthroline complex and application of prepared complex as catalyst CHINA PETROLEUM & CHEMICAL 2015-01-14 CN claimed
CN-102485732-B Preparation of butyryl-substituted 1,10-phenanthroline complex and application of prepared complex as catalyst CHINA PETROLEUM & CHEMICAL 2015-01-14 CN claimed
CN-102558241-B Preparation of 1,10-phenanthroline complex substituted by propionyl group and application of complex used as catalyst CHINA PETROLEUM & CHEMICAL 2014-11-26 CN claimed
CN-102532201-B Preparation of formoxyl substitutional 1, 10-phenanthroline coordination compound and application of prepared coordination compound as catalyst CHINA PETROLEUM & CHEMICAL 2014-11-05 CN claimed
CN-102558243-B Preparation method of alkyl-substituted 1,10-phenanthroline complex and application of complex prepared thereby as catalyst SINOPEC CORP. (CN) 2014-10-22 CN claimed
CN-102558242-B Preparation of isobutyryl substituted 1,10-phenanthroline complex and application of complex serving as catalyst SINOPEC CORP. (CN) 2014-10-22 CN claimed
CN-103804428-A Preparation method and application of complex CHINA PETROLEUM & CHEMICAL 2014-05-21 CN claimed
CN-103380137-A N ortho acyl substituted nitrogen-containing heterocyclic compound and process for preparing aminal iron (ii) complexes thereof CHINA PETROLEUM & CHEMICAL 2013-10-30 CN claimed
WO-2023185793-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF 江苏恒瑞医药股份有限公司 2023-10-05 WO disclosed
WO-2022228449-A1 PREPARATION METHOD FOR POLYIMIDE RESIN AND THIN FILM THEREOF 上海瑞暨新材料科技有限公司 2022-11-03 WO disclosed
CN-110483366-A Benzazole compounds and preparation method thereof, pharmaceutical composition and purposes INST MATERIA MEDICA CAMS 2019-11-22 CN disclosed
CN-1071429-A The N-aryl-1,2 that replaces, the preparation method of 4-triazolo pyrimidine-2-sulphonamide DOWELANCO (US) 1993-04-28 CN disclosed
CN-1030237-A BENZOHETEROCYCLIC COMPOUNDS OTSUKA PHARMA CO LTD (JP) 1989-01-11 CN disclosed
EP-0103392-A1 Fortified epoxy resin compositions and process for the preparation thereof Canadian Patents and Development Limited Société Canadienne des Brevets et d'Exploitation Limitée (CA) 1984-03-21 EP disclosed