SCHEMBL5680388

SCHEMBL5680388

[CH2]C1C(C)CCCC1c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIA4 P48058 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
SLC18A3 Q16572 1/20 0.38
MAOB P27338 8/20 0.38
MAOA P21397 7/20 0.38
KDM1A O60341 5/20 0.38
CYP2C19 P33261 4/20 0.38
CYP2B6 P20813 3/20 0.38
CYP1A2 P05177 2/20 0.38
CYP2D6 P10635 2/20 0.38
CYP2C9 P11712 2/20 0.38
LMNA P02545 2/20 0.38
TAAR1 Q96RJ0 2/20 0.38
CYP3A4 P08684 1/20 0.38
HTR1A P08908 1/20 0.38
ADRA2A P08913 1/20 0.38
CYP2A6 P11509 1/20 0.38
SLC6A2 P23975 1/20 0.38
HTR2C P28335 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16830124 0.84 MEN1 (0.46) GRIA4MEN1KMT2ASLC18A3MAOB
SCHEMBL325104 0.84 MEN1 (0.46) GRIA4MEN1KMT2ASLC18A3MAOB
SCHEMBL16830133 0.84 MEN1 (0.46) GRIA4MEN1KMT2ASLC18A3MAOB
SCHEMBL16830122 0.84 MEN1 (0.46) GRIA4MEN1KMT2ASLC18A3MAOB
SCHEMBL16830132 0.84 MEN1 (0.46) GRIA4MEN1KMT2ASLC18A3MAOB
SCHEMBL5680394 0.80 MEN1 (0.43) GRIA4MEN1KMT2ASLC18A3MAOB
SCHEMBL2496586 0.79 MEN1 (0.50) MEN1KMT2AMAOBMAOAKDM1A
SCHEMBL19207129 0.78 MEN1 (0.48) MEN1KMT2AMAOBMAOAKDM1A
SCHEMBL27969405 0.75 MEN1 (0.46) GRIA4MEN1KMT2ASLC18A3MAOB
SCHEMBL18092984 0.73 KDM1A (0.50) GRIA4MEN1KMT2AMAOBKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1184396-B1 (Meth)acrylate ester-based resin composition NIPPON CATALYTIC CHEM IND (JP) 2006-02-01 EP disclosed
US-6686413-B2 AQUEOUS DISPERSON OF A POLYMER CONTAINING UNITS OF A CYCLOHEXYLALKYL ESTER OF (METH)ACRYLIC ACID NIPPON SHOKUBAI CO., LTD. (JP) 2004-02-03 US disclosed
US-6489396-B2 A CYCLOHEXYL CONTAINING (METH)ACRYLIC ESTER-BASED POLYMER CROSSLINKED WITH A DI-FUNCTIONAL CROSSLINKING AGENT; LOW VISCOSITY RESIN FOR LOW VOLATILE ORGANIC COMPOUND (VOC)-PAINTS NIPPON SHOKUBAI CO., LTD. (JP) 2002-12-03 US disclosed
US-20020091197-A1 (Meth)acrylate ester-based resin composition NIPPON SHOKUBAI CO., LTD. (JP) 2002-07-11 US disclosed
EP-1205498-A1 (Meth)acrylate ester-based resin composition Nippon Shokubai Co., Ltd. (JP) 2002-05-15 EP disclosed
US-20020045702-A1 (Meth)acrylate ester-based resin composition NIPPON SHOKUBAI CO., LTD. (JP) 2002-04-18 US disclosed
EP-1184396-A1 (Meth)acrylate ester-based resin composition Nippon Shokubai Co., Ltd. (JP) 2002-03-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020045702-A1 (Meth)acrylate ester-based resin composition MNAT1, MAT1A, COPE GRIA4 743/4885MEN1 3687/4885KMT2A 231/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.