Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | MAP2K1 | Q02750 | 8/20 | 0.44 |
| ▸ | MAP2K2 | P36507 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5677750 | 0.87 | IDO1 (0.62) | KDM4EIDO1MAP2K1HSD17B10 | |
| SCHEMBL7623669 | 0.86 | IDO1 (0.48) | ALDH1A1GAAKDM4EGLARAB9A | |
| SCHEMBL7887582 | 0.86 | IDO1 (0.48) | ALDH1A1GAAKDM4EGLARAB9A | |
| SCHEMBL6035982 | 0.86 | IDO1 (0.61) | KDM4EIDO1MAP2K1HSD17B10 | |
| SCHEMBL5392808 | 0.85 | IDO1 (0.47) | ALDH1A1GAAKDM4EGLARAB9A | |
| SCHEMBL6035979 | 0.85 | IDO1 (0.47) | ALDH1A1GAAKDM4EGLARAB9A | |
| SCHEMBL6035710 | 0.85 | NUDT1 (0.48) | ALDH1A1GAAKDM4EGLARAB9A | |
| SCHEMBL5388573 | 0.84 | MAP2K1 (0.47) | ALDH1A1GAAKDM4EGLARAB9A | |
| SCHEMBL6035181 | 0.84 | IDO1 (0.46) | ALDH1A1GAAKDM4EGLARAB9A | |
| SCHEMBL5676362 | 0.83 | IDO1 (0.48) | ALDH1A1KDM4ERAB9ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7019033-B2 | 2-(4-bromo or 4-iodo phenylamino) benzoic acid derivatives | WARNER-LAMBERT COMPANY (US) | 2006-03-28 | — | — | US | disclosed |