Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NQO1 | P15559 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5682907 | 0.98 | SLC2A1 (0.50) | SLC2A1ALDH1A1KDM4ENQO1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7621586 | 0.98 | SLC2A1 (0.50) | SLC2A1ALDH1A1KDM4ENQO1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5682904 | 0.98 | SLC2A1 (0.50) | SLC2A1ALDH1A1KDM4ENQO1SMN1; SMN2 | |
| SCHEMBL5679109 | 0.98 | ALDH1A1 (0.49) | SLC2A1ALDH1A1KDM4ENQO1SMN1; SMN2 | |
| SCHEMBL5679115 | 0.98 | ALDH1A1 (0.49) | SLC2A1ALDH1A1KDM4ENQO1SMN1; SMN2 | |
| SCHEMBL5680729 | 0.98 | ALDH1A1 (0.49) | SLC2A1ALDH1A1KDM4ENQO1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5680830 | 0.97 | SLC2A1 (0.48) | SLC2A1ALDH1A1KDM4ENQO1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5682780 | 0.97 | SLC2A1 (0.48) | SLC2A1ALDH1A1KDM4ENQO1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5679051 | 0.97 | SLC2A1 (0.48) | SLC2A1ALDH1A1KDM4ENQO1SMN1; SMN2 | |
| SCHEMBL7789186 | 0.93 | NQO1 (0.48) | SLC2A1ALDH1A1KDM4ENQO1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144348-B1 | LTA 4 HYDROLASE INHIBITORS | BIOPROJET SOC CIV (FR) | 2006-02-08 | — | — | EP | claimed |
| EP-1144348-A3 | LTA 4? HYDROLASE INHIBITORS | BIOPROJET (FR) | 2002-09-11 | — | — | EP | claimed |
| EP-1144348-A2 | LTA 4? HYDROLASE INHIBITORS | BIOPROJET (FR) | 2001-10-17 | — | — | EP | claimed |
| WO-2000017133-A2 | LTA4 HYDROLASE INHIBITORS | BIOPROJET (FR) | 2000-03-30 | — | — | WO | claimed |
| EP-1144348-B1 | LTA 4 HYDROLASE INHIBITORS | BIOPROJET SOC CIV (FR) | 2006-02-08 | — | — | EP | disclosed |
| EP-1144348-A3 | LTA 4? HYDROLASE INHIBITORS | BIOPROJET (FR) | 2002-09-11 | — | — | EP | disclosed |
| EP-1144348-A2 | LTA 4? HYDROLASE INHIBITORS | BIOPROJET (FR) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000017133-A2 | LTA4 HYDROLASE INHIBITORS | BIOPROJET (FR) | 2000-03-30 | — | — | WO | disclosed |