Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.34 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.33 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20256032 | 0.96 | EPAS1 (0.35) | EPAS1MBTD1L3MBTL3TSHRLMNA | |
| SCHEMBL4129266 | 0.96 | MBTD1 (0.36) | EPAS1MBTD1L3MBTL3SLC6A1SLC6A11 | |
| SCHEMBL13351747 | 0.96 | MBTD1 (0.36) | EPAS1MBTD1L3MBTL3SLC6A1SLC6A11 | |
| SCHEMBL1546076 | 0.89 | EPAS1 (0.36) | EPAS1 | |
| SCHEMBL26123900 | 0.89 | MBTD1 (0.35) | EPAS1MBTD1L3MBTL3OPRM1OPRL1 | |
| SCHEMBL9142378 | 0.86 | MBTD1 (0.40) | MBTD1L3MBTL3SLC6A1SLC6A11TSHR | |
| SCHEMBL943033 | 0.86 | EPAS1 (0.33) | EPAS1 | |
| SCHEMBL2273760 | 0.86 | MBTD1 (0.40) | MBTD1L3MBTL3SLC6A1SLC6A11TSHR | |
| SCHEMBL10594 | 0.86 | EPAS1 (0.33) | EPAS1MBTD1L3MBTL3SLC6A1SLC6A11 | |
| SCHEMBL4072268 | 0.86 | MBTD1 (0.36) | MBTD1L3MBTL3SLC6A1SLC6A11TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11124518-B2 | L,2-dihydro-3H-pyrazolo[3,4-D]pyrimidin-3-one analogs | RECURIUM IP HOLDINGS, LLC (US) | 2021-09-21 | — | — | US | disclosed |
| US-20200157112-A1 | 1,2-DIHYDRO-3H-PYRAZOLO[3,4-D]PYRIMIDIN-3-ONE ANALOGS | RECURIUM IP HOLDINGS, LLC | 2020-05-21 | — | — | US | disclosed |
| US-10647989-B2 | Composition and methods for producing tobacco plants and products having reduced tobacco-specific nitrosamines (TSNAs) | ALTRIA CLIENT SERVICES LLC (US) | 2020-05-12 | — | — | US | disclosed |
| US-20100215544-A1 | HANDHELD MICROCANTILEVER-BASED SENSOR FOR DETECTING TOBACCO-SPECIFIC NITROSAMINES | PHILIP MORRIS USA INC. (US) | 2010-08-26 | — | — | US | disclosed |
| US-7709264-B2 | Handheld microcantilever-based sensor for detecting tobacco-specific nitrosamines | PHILIP MORRIS USA INC. (US) | 2010-05-04 | — | — | US | disclosed |
| US-20080102532-A1 | Handheld microcantilever-based sensor for detecting tobacco-specific nitrosamines | PHILIP MORRIS USA INC. (US) | 2008-05-01 | — | — | US | disclosed |
| EP-1060785-B1 | Interfacially polymerized, bipiperidine-polyamide membranes for reverse osmosis and/or nanofiltration and process for making the same | HYDRANAUTICS (US) | 2006-04-05 | — | — | EP | disclosed |
| EP-1047740-B1 | CURABLE RESIN COMPOSITIONS | AKZO NOBEL COATINGS INT BV (NL) | 2006-03-08 | — | — | EP | disclosed |
| US-6576297-B1 | Epoxy resin and an amine functional curing agent having heterocyclic secondary amine groups | INTERNATIONAL COATINGS LTD. (GB) | 2003-06-10 | — | — | US | disclosed |
| US-6464873-B1 | POLYFUNCTIONAL AROMATIC OR CYCLOALIPHATIC ACYL HALIDE REACTANT; HIGH FLUX RATES AND LOW PRESSURES WITH HIGH SULFATE REJECTION. | HYDRANAUTICS | 2002-10-15 | — | — | US | disclosed |
| EP-1060785-A1 | Interfacially polymerized, bipiperidine-polyamide membranes for reverse osmosis and/or nanofiltration and process for making the same | HYDRANAUTICS (US) | 2000-12-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200157112-A1 | 1,2-DIHYDRO-3H-PYRAZOLO[3,4-D]PYRIMIDIN-3-ONE ANALOGS | MKI67, BRCA1, CDK4 | EPAS1 522/4885MBTD1 2310/4885L3MBTL3 4087/4885 |
| US-11124518-B2 | L,2-dihydro-3H-pyrazolo[3,4-D]pyrimidin-3-one analogs | MKI67, BRCA1, CCND1 | EPAS1 678/4885MBTD1 2729/4885L3MBTL3 1193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.