Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 9/20 | 0.50 |
| ▸ | CA2 | P00918 | 9/20 | 0.50 |
| ▸ | CA9 | Q16790 | 9/20 | 0.50 |
| ▸ | G6PD | P11413 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3973511 | 0.80 | — | — | |
| SCHEMBL24894017 | 0.79 | CA1 (0.54) | CA1CA2CA9G6PD | |
| SCHEMBL15704433 | 0.79 | CA1 (0.54) | CA1CA2CA9G6PD | |
| Hydrochloric Acid SCHEMBL3675114 | 0.79 | PNP (0.30) | — | |
| SCHEMBL5680169 | 0.78 | CA12 (0.32) | CA1CA2CA9 | |
| SCHEMBL12616099 | 0.77 | CA1 (0.52) | CA1CA2CA9G6PD | |
| SCHEMBL13880002 | 0.76 | — | — | |
| SCHEMBL23740266 | 0.73 | G6PD (0.55) | CA1CA2CA9G6PD | |
| SCHEMBL15753669 | 0.73 | G6PD (0.55) | CA1CA2CA9G6PD | |
| SCHEMBL23689998 | 0.73 | G6PD (0.55) | CA1CA2CA9G6PD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050085432-A1 | Methods of using conjugates of saccharides and acetamidino or guanidino compounds for treating bacterial infections | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2005-04-21 | — | — | US | claimed |
| EP-1468005-A2 | METHODS OF USING CONJUGATES OF SACCHARIDES AND ACETAMIDINO OR GUANIDINO COMPOUNDS FOR TREATING BACTERIAL INFECTIONS | YEDA RESEARCH AND DEVELOPMENT Co. LTD. (IL) | 2004-10-20 | — | — | EP | claimed |
| US-6642365-B1 | Kanamycin, gentamycin or neomycin bonded to arginine; use for treatment of HIV infections and AIDS (acquired immune deficiency disease) | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2003-11-04 | — | — | US | claimed |
| WO-2003059246-A2 | METHODS OF USING CONJUGATES OF SACCHARIDES AND ACETAMIDINO OR GUANIDINO COMPOUNDS FOR TREATING BACTERIAL INFECTIONS | YEDA RESEARCH AND DEVELOPMENT CO.LTD. (IL) | 2003-07-24 | — | — | WO | claimed |
| EP-1140958-A1 | ANTI-(RETRO)VIRAL CONJUGATES OF SACCHARIDES AND ACETAMIDINO OR GUANIDINO COMPOUNDS | YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD. (IL) | 2001-10-10 | — | — | EP | claimed |
| WO-2000039139-A1 | ANTI-(RETRO)VIRAL CONJUGATES OF SACCHARIDES AND ACETAMIDINO OR GUANIDINO COMPOUNDS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2000-07-06 | — | — | WO | claimed |
| EP-1140958-B1 | ANTI-(RETRO)VIRAL CONJUGATES OF SACCHARIDES AND ACETAMIDINO OR GUANIDINO COMPOUNDS | YEDA RES & DEV (IL) | 2006-03-15 | — | — | EP | disclosed |
| US-20050085432-A1 | Methods of using conjugates of saccharides and acetamidino or guanidino compounds for treating bacterial infections | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2005-04-21 | — | — | US | disclosed |
| EP-1468005-A2 | METHODS OF USING CONJUGATES OF SACCHARIDES AND ACETAMIDINO OR GUANIDINO COMPOUNDS FOR TREATING BACTERIAL INFECTIONS | YEDA RESEARCH AND DEVELOPMENT Co. LTD. (IL) | 2004-10-20 | — | — | EP | disclosed |
| US-6642365-B1 | Kanamycin, gentamycin or neomycin bonded to arginine; use for treatment of HIV infections and AIDS (acquired immune deficiency disease) | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2003-11-04 | — | — | US | disclosed |
| WO-2003059246-A2 | METHODS OF USING CONJUGATES OF SACCHARIDES AND ACETAMIDINO OR GUANIDINO COMPOUNDS FOR TREATING BACTERIAL INFECTIONS | YEDA RESEARCH AND DEVELOPMENT CO.LTD. (IL) | 2003-07-24 | — | — | WO | disclosed |
| EP-1140958-A1 | ANTI-(RETRO)VIRAL CONJUGATES OF SACCHARIDES AND ACETAMIDINO OR GUANIDINO COMPOUNDS | YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD. (IL) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039139-A1 | ANTI-(RETRO)VIRAL CONJUGATES OF SACCHARIDES AND ACETAMIDINO OR GUANIDINO COMPOUNDS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2000-07-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050085432-A1 | Methods of using conjugates of saccharides and acetamidino or guanidino compounds for treating bacterial infections | B3GNT2, GMPS, UGT8 | CA1 1298/4885CA2 1571/4885CA9 474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.