SCHEMBL5681663

SCHEMBL5681663

COC(OC1CCC(C(=O)O)CC1)N1CCCC1

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.33
PDE4A P27815 1/20 0.32
PDE4B Q07343 1/20 0.32
PDE4C Q08493 1/20 0.32
PDE4D Q08499 1/20 0.32
LMNA P02545 3/20 0.31
HPGD P15428 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.30
PLG P00747 1/20 0.30
PLAT P00750 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1171081 0.86 SMN1; SMN2 (0.42) GAALMNAMEN1ALDH1A1KMT2A
SCHEMBL1171079 0.86 SMN1; SMN2 (0.42) GAALMNAMEN1ALDH1A1KMT2A
SCHEMBL4810824 0.82 ALDH1A1 (0.46) GAAALDH1A1
SCHEMBL3576941 0.82 ALDH1A1 (0.46) GAAALDH1A1
Trifluoroacetic Acid SCHEMBL4812305 0.78 ALDH1A1 (0.40) GAAMEN1ALDH1A1KMT2A
SCHEMBL2429488 0.78 TSHR (0.33) PDE4APDE4BPDE4CPDE4DLMNA
SCHEMBL2434333 0.76 SMN1; SMN2 (0.37) LMNAHPGDKMT2AHSD17B10
SCHEMBL2433598 0.76 SMN1; SMN2 (0.48) GAALMNAMEN1ALDH1A1KMT2A
SCHEMBL2433600 0.76 SMN1; SMN2 (0.48) GAALMNAMEN1ALDH1A1KMT2A
SCHEMBL9935314 0.76 HSD17B10 (0.36) HPGDKMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1623975-A1 PROCESS FOR PRODUCING PYRROLIDINE DERIVATIVE DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2006-02-08 EP disclosed