Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | UGT2B7 | P16662 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13681637 | 1.00 | CYP2D6 (0.47) | CYP2D6UGT2B7TP53ALDH1A1NPSR1 | |
| SCHEMBL10990788 | 0.91 | UGT2B7 (0.45) | CYP2D6UGT2B7ALDH1A1L3MBTL1TSHR | |
| SCHEMBL12469225 | 0.83 | TSHR (0.41) | CYP2D6UGT2B7ALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL27545267 | 0.82 | CYP2D6 (0.47) | CYP2D6UGT2B7ALDH1A1NPSR1THRB | |
| SCHEMBL1866738 | 0.82 | CYP2D6 (0.47) | CYP2D6UGT2B7TP53ALDH1A1NPSR1 | |
| SCHEMBL27512417 | 0.81 | EPHX2 (0.46) | TP53ALDH1A1NPSR1KDM4EGMNN | |
| SCHEMBL4452640 | 0.81 | EPHX2 (0.46) | TP53ALDH1A1NPSR1KDM4EGMNN | |
| SCHEMBL1245676 | 0.81 | CYP2D6 (0.60) | CYP2D6ALDH1A1NPSR1THRBATM | |
| SCHEMBL4818909 | 0.81 | CYP2D6 (0.46) | CYP2D6ALDH1A1NPSR1THRBATM | |
| SCHEMBL7040044 | 0.80 | UGT2B7 (0.39) | CYP2D6UGT2B7ALDH1A1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611114-A2 | AMINE-SUBSTITUTED DIPHENYLDIPHOSPHINES | Solvias AG (CH) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004089920-A2 | AMINE-SUBSTITUTED DIPHENYLDIPHOSPHINES AND THE USE THEREOF IN METAL COMPLEXES FOR ASYMMETRIC SYNTHESES | SOLVIAS AG (CH) | 2004-10-21 | — | — | WO | disclosed |