Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | TOP2A | P11388 | 3/20 | 0.55 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | ALB | P02768 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.54 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | TUBB | P07437 | 1/20 | 0.54 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.54 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.54 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.54 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.54 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.54 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.54 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5683513 | 0.89 | KDM4E (0.44) | KDM4EKMT2AALDH1A1TOP2ATOP2B | |
| Hydrochloric Acid SCHEMBL31533308 | 0.88 | KDM4E (0.64) | KDM4EKMT2AALDH1A1TOP2ATOP2B | |
| SCHEMBL29108633 | 0.86 | KDM4E (0.61) | KDM4EKMT2AALDH1A1TOP2ATOP2B | |
| SCHEMBL30542145 | 0.86 | KDM4E (0.61) | KDM4EKMT2AALDH1A1TOP2ATOP2B | |
| SCHEMBL6663406 | 0.86 | KDM4E (0.55) | KDM4EKMT2AALDH1A1TOP2ATOP2B | |
| Hydrochloric Acid SCHEMBL30542143 | 0.85 | KDM4E (0.60) | KDM4EKMT2AALDH1A1TOP2ATOP2B | |
| SCHEMBL21606774 | 0.82 | KDM4E (0.61) | KDM4EKMT2AALDH1A1TOP2ATOP2B | |
| SCHEMBL21606904 | 0.82 | KDM4E (0.67) | KDM4EKMT2AALDH1A1TOP2ATOP2B | |
| SCHEMBL23812166 | 0.81 | KDM4E (0.64) | KDM4EKMT2AALDH1A1TOP2ATOP2B | |
| SCHEMBL6665285 | 0.81 | KDM4E (0.51) | KDM4EKMT2AALDH1A1TOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831869-B1 | DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS | ELIZANOR BIOPHARMACEUTICALS IN (US) | 2006-02-08 | — | — | EP | claimed |
| US-5880111-A | CHEMOTHERAPWUTIC AGENTS; TREATING PERIODONTAL DISEASE AND URINARY TRACT INFECTIONS | FARCASIU DAN (US) | 1999-03-09 | — | — | US | claimed |