Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TOP2A | P11388 | 3/20 | 0.51 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | ALB | P02768 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TUBB | P07437 | 1/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.50 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.50 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.50 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.50 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6663406 | 0.90 | KDM4E (0.55) | KDM4EKMT2AALDH1A1TOP2ATOP2B | |
| Hydrochloric Acid SCHEMBL31533308 | 0.82 | KDM4E (0.64) | KDM4EKMT2AALDH1A1TOP2ATOP2B | |
| SCHEMBL29108633 | 0.82 | KDM4E (0.61) | KDM4EKMT2AALDH1A1TOP2ATOP2B | |
| SCHEMBL30542145 | 0.82 | KDM4E (0.61) | KDM4EKMT2AALDH1A1TOP2ATOP2B | |
| SCHEMBL6665271 | 0.81 | KDM4E (0.43) | KDM4EKMT2AALDH1A1TOP2ATOP2B | |
| Hydrochloric Acid SCHEMBL30542143 | 0.81 | KDM4E (0.60) | KDM4EKMT2AALDH1A1TOP2ATOP2B | |
| SCHEMBL6664464 | 0.81 | KDM4E (0.65) | KDM4EKMT2AALDH1A1TOP2ATOP2B | |
| SCHEMBL5683135 | 0.81 | KDM4E (0.56) | KDM4EKMT2AALDH1A1TOP2ATOP2B | |
| SCHEMBL6667316 | 0.80 | KDM4E (0.66) | KDM4EKMT2AALDH1A1TOP2ATOP2B | |
| SCHEMBL21606774 | 0.78 | KDM4E (0.61) | KDM4EKMT2AALDH1A1TOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831845-B1 | DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS | ELIZANOR BIOPHARMACEUTICALS IN (US) | 2004-09-08 | — | — | EP | disclosed |
| EP-0831845-A4 | DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS | ELIZANOR BIOPHARMACEUTICALS IN (US) | 1998-12-02 | — | — | EP | disclosed |
| EP-0831845-A1 | DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS | Elizanor Biopharmaceuticals, Inc. (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996040156-A1 | DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS | ELIZANOR BIOPHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |