Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.57 |
| ▸ | ACE | P12821 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5681153 | 0.98 | ANPEP (0.55) | ANPEPACEEPHX1LTA4HMETAP2 | |
| Hydrochloric Acid SCHEMBL7619885 | 0.98 | ANPEP (0.55) | ANPEPACEEPHX1LTA4HMETAP2 | |
| SCHEMBL13730908 | 0.82 | EPHX1 (0.61) | ANPEPEPHX1 | |
| SCHEMBL21065978 | 0.82 | EPHX1 (0.61) | ANPEPEPHX1 | |
| SCHEMBL5682810 | 0.81 | ANPEP (0.53) | ANPEPEPHX1LTA4H | |
| SCHEMBL7114970 | 0.81 | EPHX1 (0.43) | ACEEPHX1METAP2 | |
| SCHEMBL2549520 | 0.81 | EPHX1 (0.43) | ACEEPHX1METAP2 | |
| SCHEMBL1168400 | 0.81 | EPHX1 (0.43) | ACEEPHX1METAP2 | |
| Hydrochloric Acid SCHEMBL5680828 | 0.80 | ANPEP (0.52) | ANPEPEPHX1LTA4H | |
| Hydrochloric Acid SCHEMBL5680823 | 0.80 | ANPEP (0.52) | ANPEPEPHX1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144348-B1 | LTA 4 HYDROLASE INHIBITORS | BIOPROJET SOC CIV (FR) | 2006-02-08 | — | — | EP | claimed |
| EP-1144348-A3 | LTA 4? HYDROLASE INHIBITORS | BIOPROJET (FR) | 2002-09-11 | — | — | EP | claimed |
| EP-1144348-A2 | LTA 4? HYDROLASE INHIBITORS | BIOPROJET (FR) | 2001-10-17 | — | — | EP | claimed |
| WO-2000017133-A2 | LTA4 HYDROLASE INHIBITORS | BIOPROJET (FR) | 2000-03-30 | — | — | WO | claimed |
| EP-1144348-B1 | LTA 4 HYDROLASE INHIBITORS | BIOPROJET SOC CIV (FR) | 2006-02-08 | — | — | EP | disclosed |
| EP-1144348-A3 | LTA 4? HYDROLASE INHIBITORS | BIOPROJET (FR) | 2002-09-11 | — | — | EP | disclosed |
| EP-1144348-A2 | LTA 4? HYDROLASE INHIBITORS | BIOPROJET (FR) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000017133-A2 | LTA4 HYDROLASE INHIBITORS | BIOPROJET (FR) | 2000-03-30 | — | — | WO | disclosed |