Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.42 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.42 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.42 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.42 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5679867 | 0.85 | FYN (0.44) | MAPTTSHRCYP1A1CYP1A2CYP2E1 | |
| SCHEMBL5681214 | 0.81 | TP53 (0.52) | ALDH1A1MEN1KMT2ABRD4KDM4E | |
| SCHEMBL30263762 | 0.80 | TSHR (0.47) | MAPTTSHRCYP1A1CYP1A2CYP2E1 | |
| SCHEMBL28985313 | 0.80 | TSHR (0.47) | MAPTTSHRCYP1A1CYP1A2CYP2E1 | |
| SCHEMBL5679879 | 0.79 | SYK (0.47) | SYKALDH1A1BRD4KDM4ETDP1 | |
| SCHEMBL30263736 | 0.78 | CYP1A1 (0.46) | MAPTTSHRCYP1A1CYP1A2CYP2E1 | |
| SCHEMBL5679981 | 0.78 | CYP1A1 (0.46) | MAPTTSHRCYP1A1CYP1A2CYP2E1 | |
| SCHEMBL28985316 | 0.78 | CYP1A1 (0.46) | MAPTTSHRCYP1A1CYP1A2CYP2E1 | |
| SCHEMBL5682153 | 0.78 | TP53 (0.49) | TSHRCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5679729 | 0.75 | BRD4 (0.47) | MAPTTSHRALDH1A1NPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1403249-B1 | CYCLIC DIAMINE COMPOUNDS BEARING SIX-MEMBERED CYCLIC GROUPS | KOWA CO (JP) | 2006-03-15 | — | — | EP | disclosed |
| EP-1403249-A1 | CYCLIC DIAMINE COMPOUNDS BEARING SIX-MEMBERED CYCLIC GROUPS | Kowa Co., Ltd. (JP) | 2004-03-31 | — | — | EP | disclosed |
| US-6509329-B1 | Inhibitory effects on both cell adhesion and cell infiltration and is useful as a medicine for prevention or treatment of diseases such as allergy, asthma, rheumatism, arteriosclerosis and inflammation | KOWA CO., LTD. (JP) | 2003-01-21 | — | — | US | disclosed |