SCHEMBL5683279

SCHEMBL5683279

CC(C)=CC(O)C(Cl)(Br)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5682844 0.77
SCHEMBL11623256 0.77
SCHEMBL11344487 0.77
SCHEMBL8416311 0.71
SCHEMBL5700735 0.71
SCHEMBL11156614 0.71 LMNA (0.37)
SCHEMBL11151545 0.71 LMNA (0.37)
SCHEMBL7116443 0.71 LMNA (0.37)
SCHEMBL11064615 0.64
SCHEMBL5054113 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0700373-A1 PREPARATION OF HALOGENATED ALCOHOLS ZENECA LIMITED (GB) 1996-03-13 EP claimed
WO-1994027942-A1 PREPARATION OF HALOGENATED ALCOHOLS ZENECA LIMITED (GB) 1994-12-08 WO claimed
EP-0832873-B1 Preparation of cyclopropane esters SYNGENTA LTD (GB) 2006-03-08 EP disclosed
CN-1174950-C Process for producing halohydrin 2004-11-10 CN disclosed
CN-1100743-C Process for preparing halogenated alcohols ZENECA LTD (GB) 2003-02-05 CN disclosed
CN-1322703-A Process for producing halohydrin ZENECA LTD (GB) 2001-11-21 CN disclosed
EP-0793638-B1 PREPARATION OF CYCLOPROPANE ESTERS ZENECA LTD (GB) 1999-06-30 EP disclosed
CN-1220255-A Preparation of cyclopropane esters ZENECA LTD (GB) 1999-06-23 CN disclosed
EP-0700375-B1 PREPARATION OF CYCLOPROPANE ESTERS ZENECA LTD (GB) 1998-12-23 EP disclosed
EP-0700373-B1 PREPARATION OF HALOGENATED ALCOHOLS ZENECA LTD (GB) 1998-04-22 EP disclosed
EP-0700373-B1 PREPARATION OF HALOGENATED ALCOHOLS ZENECA LTD (GB) 1998-04-22 EP disclosed
CN-1124952-A Process for preparing halogenated alcohols ZENECA LTD (GB) 1996-06-19 CN disclosed
US-5527972-A Preparation and use of halogenated alcohols ZENECA LIMITED (GB) 1996-06-18 US disclosed
WO-1996016018-A1 PREPARATION OF CYCLOPROPANE ESTERS ZENECA LIMITED (GB) 1996-05-30 WO disclosed
EP-0700373-A1 PREPARATION OF HALOGENATED ALCOHOLS ZENECA LIMITED (GB) 1996-03-13 EP disclosed
EP-0700375-A1 PREPARATION OF CYCLOPROPANE ESTERS ZENECA LIMITED (GB) 1996-03-13 EP disclosed
EP-0700373-A1 PREPARATION OF HALOGENATED ALCOHOLS ZENECA LIMITED (GB) 1996-03-13 EP disclosed
WO-1994027951-A1 PREPARATION OF CYCLOPROPANE ESTERS ZENECA LIMITED (GB) 1994-12-08 WO disclosed
WO-1994027942-A1 PREPARATION OF HALOGENATED ALCOHOLS ZENECA LIMITED (GB) 1994-12-08 WO disclosed
WO-1994027942-A1 PREPARATION OF HALOGENATED ALCOHOLS ZENECA LIMITED (GB) 1994-12-08 WO disclosed