Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ESRRB | O95718 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESRRA | P11474 | 1/20 | 0.47 |
| ▸ | ESRRG | P62508 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL671029 | 0.90 | GPR119 (0.57) | GPR119MAPTLMNAALDH1A1PDK2 | |
| SCHEMBL29129953 | 0.89 | GPR119 (0.54) | GPR119MAPTLMNAALDH1A1PDK2 | |
| SCHEMBL7334881 | 0.88 | GPR119 (0.57) | GPR119MAPTLMNAALDH1A1PDK2 | |
| SCHEMBL6011698 | 0.86 | GPR119 (0.56) | GPR119MAPTLMNAALDH1A1PDK2 | |
| SCHEMBL22792199 | 0.86 | GPR119 (0.56) | GPR119MAPTLMNAALDH1A1PDK2 | |
| SCHEMBL31709335 | 0.86 | GPR119 (0.56) | GPR119MAPTLMNAALDH1A1PDK2 | |
| SCHEMBL3107402 | 0.86 | GPR119 (0.56) | GPR119MAPTLMNAALDH1A1PDK2 | |
| SCHEMBL689414 | 0.86 | GPR119 (0.56) | GPR119MAPTLMNAALDH1A1PDK2 | |
| SCHEMBL23643941 | 0.85 | GPR119 (0.55) | GPR119MAPTLMNAALDH1A1PDK2 | |
| Bromide SCHEMBL30583578 | 0.85 | GPR119 (0.55) | GPR119MAPTLMNAALDH1A1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1645556-A1 | Arylpiperazine-benzoylamide derivatives useful as pharmaceutical agents | Boehringer Ingelheim International GmbH (DE) | 2006-04-12 | — | — | EP | disclosed |