Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 7/20 | 0.40 |
| ▸ | HRH1 | P35367 | 7/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7624822 | 0.98 | HRH3 (0.43) | HRH3MMP2MMP3MAPTALDH1A1 | |
| SCHEMBL5681317 | 0.83 | HRH3 (0.46) | HRH3MMP2MMP3MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL7616382 | 0.82 | HRH3 (0.44) | HRH3MMP2MMP3MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL5681290 | 0.82 | HRH3 (0.44) | HRH3MMP2MMP3MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL5681304 | 0.82 | HRH3 (0.44) | HRH3MMP2MMP3MAPTALDH1A1 | |
| SCHEMBL5682901 | 0.82 | HRH3 (0.48) | HRH3MMP2MMP3MAPTALDH1A1 | |
| SCHEMBL5678787 | 0.81 | ALDH1A1 (0.47) | MAPTALDH1A1KDM4E | |
| SCHEMBL5679251 | 0.81 | KCNA3 (0.55) | ALDH1A1HDAC1HDAC2 | |
| SCHEMBL5681083 | 0.81 | KCNA3 (0.55) | ALDH1A1HDAC1HDAC2 | |
| Hydrochloric Acid SCHEMBL7617352 | 0.81 | HRH3 (0.47) | HRH3MMP2MMP3MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144348-B1 | LTA 4 HYDROLASE INHIBITORS | BIOPROJET SOC CIV (FR) | 2006-02-08 | — | — | EP | claimed |