Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.68 |
| ▸ | HPGD | P15428 | 5/20 | 0.68 |
| ▸ | HTT | P42858 | 4/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | BRD4 | O60885 | 1/20 | 0.68 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | RAD52 | P43351 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7824014 | 0.88 | DRD3 (0.84) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL5679313 | 0.88 | DRD3 (0.65) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL2739071 | 0.86 | DRD3 (0.77) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL7546026 | 0.85 | DRD3 (0.69) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL7538950 | 0.84 | DRD3 (0.77) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL5007468 | 0.84 | KDM4E (0.75) | HSD17B10KDM4EALDH1A1HPGDHTT | |
| Pefloxacin SCHEMBL29351730 | 0.84 | DRD3 (1.00) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL10738656 | 0.84 | DRD3 (0.84) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| Pefloxacin SCHEMBL34292 | 0.84 | DRD3 (1.00) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| Pefloxacin SCHEMBL28251251 | 0.84 | DRD3 (1.00) | DRD3HSD17B10KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831869-B1 | DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS | ELIZANOR BIOPHARMACEUTICALS IN (US) | 2006-02-08 | — | — | EP | claimed |