Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGPL1 | O95470 | 5/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.35 |
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | HTR7 | P34969 | 3/20 | 0.34 |
| ▸ | HTR1D | P28221 | 2/20 | 0.34 |
| ▸ | HTR1B | P28222 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 6/20 | 0.33 |
| ▸ | DRD3 | P35462 | 4/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5684118 | 1.00 | SGPL1 (0.35) | SGPL1S1PR1HTR1AHTR7HTR1D | |
| SCHEMBL5683896 | 0.90 | HTR1A (0.35) | SGPL1S1PR1HTR1AHTR7HTR1D | |
| SCHEMBL5683905 | 0.90 | HTR1A (0.35) | SGPL1S1PR1HTR1AHTR7HTR1D | |
| SCHEMBL5683988 | 0.89 | HTR1D (0.36) | SGPL1S1PR1HTR1AHTR7HTR1D | |
| SCHEMBL5684009 | 0.89 | HTR1D (0.36) | SGPL1S1PR1HTR1AHTR7HTR1D | |
| SCHEMBL5683995 | 0.89 | HTR1D (0.36) | SGPL1S1PR1HTR1AHTR7HTR1D | |
| SCHEMBL5684003 | 0.89 | HTR1D (0.36) | SGPL1S1PR1HTR1AHTR7HTR1D | |
| SCHEMBL5684370 | 0.89 | SGPL1 (0.35) | SGPL1S1PR1HTR1AHTR7HTR1D | |
| SCHEMBL5684386 | 0.89 | SGPL1 (0.35) | SGPL1S1PR1HTR1AHTR7HTR1D | |
| SCHEMBL5684375 | 0.89 | SGPL1 (0.35) | SGPL1S1PR1HTR1AHTR7HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067179-B1 | Fused ring compound | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2006-06-27 | — | — | US | disclosed |
| EP-1201632-B1 | FUSED RING COMPOUND | DAINIPPON INK & CHEMICALS (JP) | 2006-03-29 | — | — | EP | disclosed |
| EP-1201632-A1 | FUSED RING COMPOUND | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2002-05-02 | — | — | EP | disclosed |