Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | MARK3 | P27448 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.38 |
| ▸ | STK3 | Q13188 | 1/20 | 0.38 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3158489 | 0.94 | TSHR (0.42) | GSK3BCHRNA7HRH3TSHRJAK2 | |
| SCHEMBL3158383 | 0.94 | TSHR (0.42) | GSK3BCHRNA7HRH3TSHRJAK2 | |
| SCHEMBL7664905 | 0.89 | NCEH1 (0.40) | TSHRNCEH1KIF11 | |
| SCHEMBL3170923 | 0.86 | GSK3B (0.37) | GSK3BCHRNA7TSHRNCEH1SERPINE1 | |
| SCHEMBL3168983 | 0.86 | PCSK9 (0.43) | GSK3BCHRNA7HRH3TSHRJAK2 | |
| SCHEMBL3166994 | 0.86 | PCSK9 (0.43) | GSK3BCHRNA7HRH3TSHRJAK2 | |
| SCHEMBL3165349 | 0.86 | SLC13A5 (0.43) | GSK3BCHRNA7TSHRJAK2ROCK2 | |
| SCHEMBL3162115 | 0.86 | SLC13A5 (0.43) | GSK3BCHRNA7TSHRJAK2ROCK2 | |
| SCHEMBL6059636 | 0.85 | GSK3B (0.39) | GSK3BCHRNA7TSHRSERPINE1GRM2 | |
| SCHEMBL5684909 | 0.85 | GRM2 (0.36) | GSK3BCHRNA7TSHRNCEH1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067179-B1 | Fused ring compound | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2006-06-27 | — | — | US | disclosed |
| EP-1201632-B1 | FUSED RING COMPOUND | DAINIPPON INK & CHEMICALS (JP) | 2006-03-29 | — | — | EP | disclosed |
| EP-1201632-A1 | FUSED RING COMPOUND | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2002-05-02 | — | — | EP | disclosed |