Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | TLR4 | O00206 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5884833 | 1.00 | LMNA (0.38) | LMNAPLGPLATTLR4ANPEP | |
| SCHEMBL5884828 | 1.00 | LMNA (0.38) | LMNAPLGPLATTLR4ANPEP | |
| SCHEMBL5599221 | 0.92 | LMNA (0.41) | LMNAPLGPLATTLR4ANPEP | |
| SCHEMBL6459367 | 0.92 | LMNA (0.41) | LMNAPLGPLATTLR4ANPEP | |
| SCHEMBL5599223 | 0.92 | LMNA (0.41) | LMNAPLGPLATTLR4ANPEP | |
| SCHEMBL10828238 | 0.91 | HTT (0.43) | LMNAPLGPLATTLR4MAPK1 | |
| Hydrochloric Acid SCHEMBL10828262 | 0.89 | HTT (0.42) | LMNAPLGPLATTLR4MAPK1 | |
| SCHEMBL9037337 | 0.84 | LMNA (0.47) | LMNAPLGPLATTLR4ANPEP | |
| SCHEMBL6461806 | 0.83 | PLG (0.44) | LMNAPLGPLATTLR4ANPEP | |
| SCHEMBL7917053 | 0.83 | PLG (0.44) | LMNAPLGPLATTLR4ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1201632-B1 | FUSED RING COMPOUND | DAINIPPON INK & CHEMICALS (JP) | 2006-03-29 | — | — | EP | disclosed |